Massachusetts Institute of Technology

City Cambridge
State Massachusetts
  1. 2020
  2. Published

    The physical mechanisms of Drosophila gastrulation: Mesoderm and endoderm invagination

    Adam C. Martin, Jan 1 2020, In : Genetics. 214, 3, p. 543-560 18 p.

    Research output: Contribution to journalArticle

  3. Published

    The cellular and molecular mechanisms that establish the mechanics of Drosophila gastrulation

    Clint S. Ko & Adam C. Martin, 2020, Current Topics in Developmental Biology. Solnica-Krezel, L. (ed.). Academic Press Inc., p. 141-165 25 p. (Current Topics in Developmental Biology; vol. 136).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  4. 2019
  5. Published

    Ventricular stroke work and vascular impedance refine the characterization of patients with aortic stenosis

    Eyal Ben-Assa, Jonathan Brown, Zahra Keshavarz-Motamed, Jose M. De La Torre Hernandez, Benjamin Leiden, Max Olender & 8 others, Faouzi Kallel, Igor F. Palacios, Ignacio Inglessis, Jonathan J. Passeri, Pinak B. Shah, Sammy Elmariah, Martin B. Leon & Elazer R. Edelman, Sep 11 2019, In : Science Translational Medicine. 11, 509, eaaw0181.

    Research output: Contribution to journalArticle

  6. Published

    Microtubules promote intercellular contractile force transmission during tissue folding

    Clint S. Ko, Vardges Tserunyan & Adam C. Martin, Aug 5 2019, In : Journal of Cell Biology. 218, 8, p. 2726-2742 17 p.

    Research output: Contribution to journalArticle

  7. Published

    Activated T-effector seeds: Cultivating atherosclerotic plaque through alternative activation

    Maria M. Xu, Patrick A. Murphy & Anthony T. Vella, Jun 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 6, p. H1354-H1365

    Research output: Contribution to journalReview article

  8. Published

    Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci

    M. Xu Maria, Antoine Ménoret, Sarah Anne E. Nicholas, Sebastian Günther, Eric J. Sundberg, Beiyan Zhou & 3 others, Annabelle Rodriguez, Patrick A. Murphy & Anthony T. Vella, Jun 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 6, p. H1480-H1494

    Research output: Contribution to journalArticle

  9. Published

    Decellularized neonatal cardiac extracellular matrix prevents widespread ventricular remodeling in adult mammals after myocardial infarction

    Zhouguang Wang, Daniel W. Long, Yan Huang, William C.W. Chen, Kang Kim & Yadong Wang, Mar 15 2019, In : Acta Biomaterialia. 87, p. 140-151 12 p.

    Research output: Contribution to journalArticle

  10. Published

    H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration

    Raz Ben-Yair, Vincent L. Butty, Michele Busby, Yutong Qiu, Stuart S. Levine, Alon Goren & 3 others, Laurie A. Boyer, C. Geoffrey Burns & Caroline E. Burns, Jan 1 2019, In : Development (Cambridge). 146, 19, dev178632.

    Research output: Contribution to journalArticle

  11. 2018
  12. Published

    A fluorescent microbead-based microfluidic immunoassay chip for immune cell cytokine secretion quantification

    Xin Cui, Ya Liu, Dinglong Hu, Weiyi Qian, Chung Tin, Dong Sun & 2 others, Weiqiang Chen & Raymond H.W. Lam, Feb 7 2018, In : Lab on a Chip. 18, 3, p. 522-531 10 p.

    Research output: Contribution to journalArticle

  13. Published

    A controlled release system for simultaneous delivery of three human perivascular stem cell-derived factors for tissue repair and regeneration

    Nurlan Mansurov, William C.W. Chen, Hassan Awada, Johnny Huard, Yadong Wang & Arman Saparov, Feb 1 2018, In : Journal of Tissue Engineering and Regenerative Medicine. 12, 2, p. e1164-e1172

    Research output: Contribution to journalArticle

  14. 2017
  15. Published

    Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4

    Benjamin Steinhorn, Juliano L. Sartoretto, Andrea Sorrentino, Natalia Romero, Hermann Kalwa, E. Dale Abel & 1 others, Thomas Michel, Dec 2017, In : Free Radical Biology and Medicine. 113, p. 16-25 10 p.

    Research output: Contribution to journalArticle

  16. Published

    Actomyosin-based tissue folding requires a multicellular myosin gradient

    Natalie C. Heer, Pearson W. Miller, Soline Chanet, Norbert Stoop, Jörn Dunkel & Adam C. Martin, Jun 1 2017, In : Journal of cell science. 130, 11, p. 1876-1886 11 p.

    Research output: Contribution to journalArticle

  17. Published

    Actomyosin meshwork mechanosensing enables tissue shape to orient cell force

    Soline Chanet, Callie J. Miller, Eeshit Dhaval Vaishnav, Bard Ermentrout, Lance A. Davidson & Adam C. Martin, May 15 2017, In : Nature communications. 8, 15014.

    Research output: Contribution to journalArticle

  18. Published

    Skeletal and cardiac muscle pericytes: Functions and therapeutic potential

    Iain R. Murray, James E. Baily, William C.W. Chen, Ayelet Dar, Zaniah N. Gonzalez, Andrew R. Jensen & 3 others, Frank A. Petrigliano, Arjun Deb & Neil C. Henderson, Mar 1 2017, In : Pharmacology and Therapeutics. 171, p. 65-74 10 p.

    Research output: Contribution to journalReview article

  19. Published

    Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing

    Christopher A. Werley, Miao Ping Chien, Jellert Gaublomme, Karthik Shekhar, Vincent Butty, B. Alexander Yi & 5 others, Joel M. Kralj, William Bloxham, Laurie A. Boyer, Aviv Regev & Adam E. Cohen, Mar 2017, In : PloS one. 12, 3, e0172671.

    Research output: Contribution to journalArticle

  20. 2016
  21. Published

    Drosophila non-muscle myosin II motor activity determines the rate of tissue folding

    Claudia G. Vasquez, Sarah M. Heissler, Neil Billington, James R. Sellers & Adam C. Martin, Dec 30 2016, In : eLife. 5, DECEMBER2016, e20828.

    Research output: Contribution to journalArticle

  22. Published

    Apical Sarcomere-like Actomyosin Contracts Nonmuscle Drosophila Epithelial Cells

    Jonathan S. Coravos & Adam Martin, Nov 7 2016, In : Developmental cell. 39, 3, p. 346-358 13 p.

    Research output: Contribution to journalArticle

  23. Published

    Loss of Gα12/13 exacerbates apical area dependence of actomyosin contractility

    Shicong Xie, Frank M. Mason & Adam C. Martin, Nov 7 2016, In : Molecular biology of the cell. 27, 22, p. 3526-3536 11 p.

    Research output: Contribution to journalArticle

  24. Published

    Isolation of perivascular multipotent precursor cell populations from human cardiac tissue

    James E. Baily, William C.W. Chen, Nusrat Khan, Iain R. Murray, Zaniah N. González Galofre, Johnny Huard & 1 others, Bruno Péault, Oct 8 2016, In : Journal of Visualized Experiments. 2016, 116, e54252.

    Research output: Contribution to journalArticle

  25. Published

    A G-Rich Motif in the lncRNA Braveheart Interacts with a Zinc-Finger Transcription Factor to Specify the Cardiovascular Lineage

    Zhihong Xue, Scott Hennelly, Boryana Doyle, Arune A. Gulati, Irina V. Novikova, Karissa Y. Sanbonmatsu & 1 others, Laurie A. Boyer, Oct 6 2016, In : Molecular cell. 64, 1, p. 37-50 14 p.

    Research output: Contribution to journalArticle

  26. Published

    52 Genetic Loci Influencing Myocardial Mass

    Pim van der Harst, Jessica van Setten, Niek Verweij, Georg Vogler, Lude Franke, Matthew T. Maurano & 154 others, Xinchen Wang, Irene Mateo Leach, Mark Eijgelsheim, Nona Sotoodehnia, Caroline Hayward, Rossella Sorice, Osorio Meirelles, Leo Pekka Lyytikäinen, Ozren Polašek, Toshiko Tanaka, Dan E. Arking, Sheila Ulivi, Stella Trompet, Martina Müller-Nurasyid, Albert V. Smith, Marcus Dörr, Kathleen F. Kerr, Jared W. Magnani, Fabiola Del Greco M., Weihua Zhang, Ilja M. Nolte, Claudia T. Silva, Sandosh Padmanabhan, Vinicius Tragante, Tõnu Esko, Gonçalo R. Abecasis, Michiel E. Adriaens, Karl Andersen, Phil Barnett, Joshua C. Bis, Rolf Bodmer, Brendan M. Buckley, Harry Campbell, Megan V. Cannon, Aravinda Chakravarti, Lin Y. Chen, Alessandro Delitala, Richard B. Devereux, Pieter A. Doevendans, Anna F. Dominiczak, Luigi Ferrucci, Ian Ford, Christian Gieger, Tamara B. Harris, Eric Haugen, Matthias Heinig, Dena G. Hernandez, Hans L. Hillege, Joel N. Hirschhorn, Albert Hofman, Norbert Hubner, Shih Jen Hwang, Annamaria Iorio, Mika Kähönen, Manolis Kellis, Ivana Kolcic, Ishminder K. Kooner, Jaspal S. Kooner, Jan A. Kors, Edward G. Lakatta, Kasper Lage, Lenore J. Launer, Daniel Levy, Alicia Lundby, Peter W. Macfarlane, Dalit May, Thomas Meitinger, Andres Metspalu, Stefania Nappo, Silvia Naitza, Shane Neph, Alex S. Nord, Teresa Nutile, Peter M. Okin, Jesper V. Olsen, Ben A. Oostra, Josef M. Penninger, Len A. Pennacchio, Tune H. Pers, Siegfried Perz, Annette Peters, Yigal M. Pinto, Arne Pfeufer, Maria Grazia Pilia, Peter P. Pramstaller, Bram P. Prins, Olli T. Raitakari, Soumya Raychaudhuri, Ken M. Rice, Elizabeth J. Rossin, Jerome I. Rotter, Sebastian Schafer, David Schlessinger, Carsten O. Schmidt, Jobanpreet Sehmi, Herman H.W. Silljé, Gianfranco Sinagra, Moritz F. Sinner, Kamil Slowikowski, Elsayed Z. Soliman, Timothy D. Spector, Wilko Spiering, John A. Stamatoyannopoulos, Ronald P. Stolk, Konstantin Strauch, Sian Tsung Tan, Kirill V. Tarasov, Bosco Trinh, Andre G. Uitterlinden, Malou van den Boogaard, Cornelia M. van Duijn, Wiek H. van Gilst, Jorma S. Viikari, Peter M. Visscher, Veronique Vitart, Uwe Völker, Melanie Waldenberger, Christian X. Weichenberger, Harm Jan Westra, Cisca Wijmenga, Bruce H. Wolffenbuttel, Jian Yang, Connie R. Bezzina, Patricia B. Munroe, Harold Snieder, Alan F. Wright, Igor Rudan, Laurie A. Boyer, Folkert W. Asselbergs, Dirk J. van Veldhuisen, Bruno H. Stricker, Bruce M. Psaty, Marina Ciullo, Serena Sanna, Terho Lehtimäki, James F. Wilson, Stefania Bandinelli, Alvaro Alonso, Paolo Gasparini, J. Wouter Jukema, Stefan Kääb, Vilmundur Gudnason, Stephan B. Felix, Susan R. Heckbert, Rudolf A. de Boer, Christopher Newton-Cheh, Andrew A. Hicks, John C. Chambers, Yalda Jamshidi, Axel Visel, Vincent M. Christoffels, Aaron Isaacs, Nilesh J. Samani & Paul I.W. de Bakker, Sep 27 2016, In : Journal of the American College of Cardiology. 68, 13, p. 1435-1448 14 p.

    Research output: Contribution to journalArticle

  27. Published

    Elimination of Transcoarctation Pressure Gradients Has No Impact on Left Ventricular Function or Aortic Shear Stress After Intervention in Patients With Mild Coarctation

    Zahra Keshavarz-Motamed, Farhad Rikhtegar Nezami, Ramon A. Partida, Kenta Nakamura, Pedro Vinícius Staziaki, Eyal Ben-Assa & 3 others, Brian Ghoshhajra, Ami B. Bhatt & Elazer R. Edelman, Sep 26 2016, In : JACC: Cardiovascular Interventions. 9, 18, p. 1953-1965 13 p.

    Research output: Contribution to journalArticle

  28. Published

    Abl suppresses cell extrusion and intercalation during epithelium folding

    Jeanne N. Jodoin & Adam Martin, Sep 15 2016, In : Molecular biology of the cell. 27, 18, p. 2822-2832 11 p.

    Research output: Contribution to journalArticle

  29. Published

    Polycations and their biomedical applications

    Kyobum Kim, William C.W. Chen, Yunhoe Heo & Yadong Wang, Sep 1 2016, In : Progress in Polymer Science. 60, p. 18-50 33 p.

    Research output: Contribution to journalReview article

  30. Published

    Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram

    Lifelines Cohort Study Lifelines Cohort Study & LifeLines GWAS Working Group LifeLines GWAS Working Group, May 15 2016, In : Human molecular genetics. 25, 10, p. 2093-2103 11 p.

    Research output: Contribution to journalArticle

  31. Published

    Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures

    Xinchen Wang, Nathan R. Tucker, Gizem Rizki, Robert Mills, Peter H.L. Krijger, Elzo De Wit & 13 others, Vidya Subramanian, Eric Bartell, Xinh Xinh Nguyen, Jiangchuan Ye, Jordan Leyton-Mange, Elena V. Dolmatova, Pim Van Der Harst, Wouter De Laat, Patrick T. Ellinor, Christopher Newton-Cheh, David J. Milan, Manolis Kellis & Laurie A. Boyer, May 10 2016, In : eLife. 5, MAY2016, e10557.

    Research output: Contribution to journalArticle

  32. Published

    Epithelial Contractility: A Crowning Achievement

    Jeanne N. Jodoin & Adam C. Martin, Apr 4 2016, In : Developmental cell. 37, 1, p. 3-4 2 p.

    Research output: Contribution to journalShort survey

  33. Published

    Force transmission in epithelial tissues

    Claudia G. Vasquez & Adam C. Martin, Mar 1 2016, In : Developmental Dynamics. 245, 3, p. 361-371 11 p.

    Research output: Contribution to journalReview article

  34. Published

    Mouse models of cerebral arteriovenous malformation

    Corinne M. Nielsen, Lawrence Huang, Patrick A. Murphy, Michael T. Lawton & Rong A. Wang, Jan 1 2016, In : Stroke. 47, 1, p. 293-300 8 p.

    Research output: Contribution to journalArticle

  35. Published

    RhoA GTPase inhibition organizes contraction during epithelial morphogenesis

    Frank M. Mason, Shicong Xie, Claudia G. Vasquez, Michael Tworoger & Adam C. Martin, Jan 1 2016, In : Journal of Cell Biology. 214, 5, p. 603-617 15 p.

    Research output: Contribution to journalArticle

  36. 2015
  37. Published

    Stable Force Balance between Epithelial Cells Arises from F-Actin Turnover

    Jeanne N. Jodoin, Jonathan S. Coravos, Soline Chanet, Claudia G. Vasquez, Michael Tworoger, Elena R. Kingston & 3 others, Lizabeth A. Perkins, Norbert Perrimon & Adam C. Martin, Dec 21 2015, In : Developmental cell. 35, 6, p. 685-697 13 p.

    Research output: Contribution to journalArticle

  38. Published

    Controlled dual delivery of fibroblast growth factor-2 and Interleukin-10 by heparin-based coacervate synergistically enhances ischemic heart repair

    William C.W. Chen, Brandon G. Lee, Dae Woo Park, Kyobum Kim, Hunghao Chu, Kang Kim & 2 others, Johnny Huard & Yadong Wang, Dec 2015, In : Biomaterials. 72, p. 138-151 14 p.

    Research output: Contribution to journalArticle

  39. Published

    NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair

    J. D. Proto, Y. Tang, A. Lu, W. C.W. Chen, E. Stahl, M. Poddar & 8 others, S. A. Beckman, P. D. Robbins, L. J. Nidernhofer, K. Imbrogno, T. Hannigan, W. M. Mars, B. Wang & J. Huard, Apr 23 2015, In : Cell Death and Disease. 6, 4, e1730.

    Research output: Contribution to journalArticle

  40. Published

    Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors

    Patrick Andries Murphy, Shahinoor Begum & Richard O. Hynes, Mar 25 2015, In : PloS one. 10, 3, e0120872.

    Research output: Contribution to journalArticle

  41. Published

    Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination

    Kirk D.C. Jensen, Ana Camejo, Mariane B. Melo, Cynthia Cordeiro, Lindsay Julien, Gijsbert M. Grotenbreg & 4 others, Eva Maria Frickel, Hidde L. Ploegh, Lucy Young & Jeroen P.J. Saeij, Feb 24 2015, In : mBio. 6, 2, e02280-14.

    Research output: Contribution to journalArticle

  42. Published

    Human myocardial pericytes: Multipotent mesodermal precursors exhibiting cardiac specificity

    William C.W. Chen, James E. Baily, Mirko Corselli, Mary E. Díaz, Bin Sun, Guosheng Xiang & 3 others, Gillian A. Gray, Johnny Huard & Bruno Péault, Feb 1 2015, In : STEM CELLS. 33, 2, p. 557-573 17 p.

    Research output: Contribution to journalArticle

  43. Published

    Nature or Nurture: Innate versus Cultured Mesenchymal Stem Cells for Tissue Regeneration

    Alvaro Santamaria, Greg Asatrian, William C.W. Chen, Aaron W. James, Winters Hardy, Kang Ting & 3 others, Arnold I. Caplan, Chia Soo & Bruno Péault, Jan 1 2015, Translating Regenerative Medicine to the Clinic. Elsevier Inc., p. 227-240 14 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  44. Published

    Regenerative translation of human blood-vessel-derived MSC precursors

    William C.W. Chen, Bruno Péault & Johnny Huard, Jan 1 2015, In : Stem Cells International. 2015, 375187.

    Research output: Contribution to journalReview article

  45. 2014
  46. Published

    Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels

    Patrick A. Murphy, Tyson N. Kim, Lawrence Huang, Corinne M. Nielsen, Michael T. Lawton, Ralf H. Adams & 2 others, Chris B. Schaffer & Rong A. Wang, Dec 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 50, p. 18007-18012 6 p.

    Research output: Contribution to journalArticle

  47. Published

    Gold nanoparticle-decellularized matrix hybrids for cardiac tissue engineering

    Michal Shevach, Sharon Fleischer, Assaf Shapira & Tal Dvir, Oct 8 2014, In : Nano letters. 14, 10, p. 5792-5796 5 p.

    Research output: Contribution to journalArticle

  48. Published

    Alternative splicing of endothelial fibronectin is induced by disturbed hemodynamics and protects against hemorrhage of the vessel wall

    Patrick A. Murphy & Richard O. Hynes, Sep 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 9, p. 2042-2050 9 p.

    Research output: Contribution to journalArticle

  49. Published

    Role of donor and host cells in muscle-derived stem cell-mediated bone repair: Differentiation vs. paracrine effects

    Xueqin Gao, Arvydas Usas, Jonathan D. Proto, Aiping Lu, James H. Cummins, Alexander Proctor & 2 others, Chien Wen Chen & Johnny Huard, Aug 2014, In : FASEB Journal. 28, 8, p. 3792-3809 18 p.

    Research output: Contribution to journalArticle

  50. Published

    Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium

    Hermann Kalwa, Juliano L. Sartoretto, Roberta Martinelli, Natalia Romero, Benjamin Steinhorn, Ming Tao & 3 others, C Keith OZAKI, Christopher Vincent Carman & Thomas Michel, Mar 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 9, p. 3383-3388 6 p.

    Research output: Contribution to journalArticle

  51. Published

    Machine learning classification of cell-specific cardiac enhancers uncovers developmental subnetworks regulating progenitor cell division and cell fate specification

    Shaad Mohiuddin Ahmad, Brian W. Busser, Di Huang, Elizabeth J. Cozart, Sébastien Michaud, Xianmin Zhu & 5 others, Neal Jeffries, Anton Aboukhalil, Martha L. Bulyk, Ivan Ovcharenko & Alan M. Michelson, Feb 15 2014, In : Development (Cambridge). 141, 4, p. 878-888 11 p.

    Research output: Contribution to journalArticle

  52. Published

    Identification of three novel Toxoplasma gondii rhoptry proteins

    Ana Camejo, Daniel A. Gold, Diana Lu, Kiva McFetridge, Lindsay Julien, Ninghan Yang & 2 others, Kirk D.C. Jensen & Jeroen P.J. Saeij, Feb 1 2014, In : International Journal for Parasitology. 44, 2, p. 147-160 14 p.

    Research output: Contribution to journalArticle

  53. Published

    Toxoplasma gondii inhibits gamma interferon (IFN-γ)-and IFN-β-induced host cell STAT1 transcriptional activity by increasing the association of STAT1 with DNA

    Emily E. Rosowski, Quynh P. Nguyen, Ana Camejo, Eric Spooner & Jeroen P.J. Saeija, Feb 1 2014, In : Infection and immunity. 82, 2, p. 706-719 14 p.

    Research output: Contribution to journalArticle

  54. Published

    Distal enhancers: New insights into heart development and disease

    Joseph A. Wamstad, Xinchen Wang, Olukunle O. Demuren & Laurie A Boyer, Jan 1 2014, In : Trends in Cell Biology. 24, 5, p. 294-302 9 p.

    Research output: Contribution to journalReview article

  55. Published

    Fabrication of omentum-based matrix for engineering vascularized cardiac tissues

    Michal Shevach, Neta Soffer-Tsur, Sharon Fleischer, Assaf Shapira & Tal Dvir, Jan 1 2014, In : Biofabrication. 6, 2, 024101.

    Research output: Contribution to journalArticle

  56. Published

    Lipid emulsion rapidly restores contractility in stunned mouse cardiomyocytes: A comparison with therapeutic hypothermia

    Jing Li, Michael Robert Fettiplace, Sy Jou Chen, Benjamin Steinhorn, Zuohui Shao, Xiangdong Zhu & 4 others, Changqing Li, Shaun Harty, Guy Weinberg & Terry L. Van Den Hoek, Jan 1 2014, In : Critical care medicine. 42, 12, p. e734-e740

    Research output: Contribution to journalArticle

  57. Published

    Isolation of blood-vessel-derived multipotent precursors from human skeletal muscle

    William C W Chen, Arman Saparov, Mirko Corselli, Mihaela Crisan, Bo Zheng, Bruno Péault & 1 others, Johnny Huard, 2014, In : Journal of visualized experiments : JoVE. 90, p. e51195

    Research output: Contribution to journalArticle

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