University of Rochester Medical Center

City Rochester
State New York
  1. 2020
  2. Published

    Optogenetic control of mitochondrial protonmotive force to impact cellular stress resistance

    Brandon J. Berry, Adam J. Trewin, Alexander S. Milliken, Aksana Baldzizhar, Andrea M. Amitrano, Yunki Lim & 2 others, Minsoo Kim & Andrew P. Wojtovich, Apr 3 2020, In : EMBO Reports. 21, 4, e49113.

    Research output: Contribution to journalArticle

  3. Published

    Conformational spread and dynamics in allostery of NMDA receptors

    Ryan J. Durham, Nabina Paudyal, Elisa Carrillo, Nidhi Kaur Bhatia, David M. Maclean, Vladimir Berka & 3 others, Drew M. Dolino, Alemayehu A. Gorfe & Vasanthi Jayaraman, Feb 18 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 7, p. 3839-3847 9 p.

    Research output: Contribution to journalArticle

  4. Published

    Coronary disease-associated gene TCF21 inhibits smooth muscle cell differentiation by blocking the myocardin-serum response factor pathway

    Manabu Nagao, Qing Lyu, Quanyi Zhao, Robert C. Wirka, Joetsaroop Bagga, Trieu Nguyen & 5 others, Paul Cheng, Juyong Brian Kim, Milos Pjanic, Joseph M. Miano & Thomas Quertermous, Feb 14 2020, In : Circulation research. p. 517-529 13 p.

    Research output: Contribution to journalArticle

  5. Published

    Regulation of SRF protein stability by an autophagy-dependent pathway

    Jinque Luo, Felix Q. Jin, Meimei Yin & Zheng Gen Jin, Jan 8 2020, In : Biochemical and Biophysical Research Communications. 521, 2, p. 279-284 6 p.

    Research output: Contribution to journalArticle

  6. Published

    Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture

    Wei Luo, Yidan Wang, Lin Zhang, Pingping Ren, Chen Zhang, Yanming Li & 15 others, Alon R. Azares, Michelle Zhang, Jiao Guo, Ketan B. Ghaghada, Zbigniew A. Starosolski, Kimal Rajapakshe, Cristian Coarfa, Yumei Li, Rui Chen, Keigi Fujiwara, Jun Ichi Abe, Joseph S. Coselli, DIanna M. Milewicz, Scott A. Lemaire & Ying H. Shen, Jan 7 2020, In : Circulation. p. 42-66 25 p.

    Research output: Contribution to journalArticle

  7. Published

    Mechanism of modulation of AMPA receptors by TARP-γ8

    Elisa Carrillo, Sana A. Shaikh, Vladimir Berka, Ryan J. Durham, Douglas B. Litwin, Garam Lee & 3 others, David M. MacLean, Linda M. Nowak & Vasanthi Jayaraman, Jan 6 2020, In : Journal of General Physiology. 152, 1

    Research output: Contribution to journalArticle

  8. Published

    Curcumin, the golden spice in treating cardiovascular diseases

    Hong Li, Antoni Sureda, Hari Prasad Devkota, Valeria Pittalà, Davide Barreca, Ana Sanches Silva & 3 others, Devesh Tewari, Suowen Xu & Seyed Mohammad Nabavi, Jan 1 2020, In : Biotechnology Advances. 38, 107343.

    Research output: Contribution to journalReview article

  9. Published

    VEGF signalling enhances lesion burden in KRIT1 deficient mice

    Peter V. DiStefano & Angela J. Glading, Jan 1 2020, In : Journal of cellular and molecular medicine. 24, 1, p. 632-639 8 p.

    Research output: Contribution to journalArticle

  10. Published

    PKCβII specifically regulates KCNQ1/KCNE1 channel membrane localization

    Chen Braun, Xiaorong Xu Parks, Haani Qudsi & Coeli M. Lopes, Jan 2020, In : Journal of Molecular and Cellular Cardiology. 138, p. 283-290 8 p.

    Research output: Contribution to journalArticle

  11. 2019
  12. Published

    A simple protocol for isolating mouse lung endothelial cells

    Jinping Wang, Niu Niu, Suowen Xu & Zheng Gen Jin, Dec 1 2019, In : Scientific reports. 9, 1, 1458.

    Research output: Contribution to journalArticle

  13. Published

    Cardiac interstitial tetraploid cells can escape replicative senescence in rodents but not large mammals

    Kathleen M. Broughton, Tiffany Khieu, Nicky Nguyen, Michael Rosa, Sadia Mohsin, Pearl Quijada & 11 others, Bingyan J. Wang, Oscar H. Echeagaray, Dieter A. Kubli, Taeyong Kim, Fareheh Firouzi, Megan M. Monsanto, Natalie A. Gude, Robert M. Adamson, Walter P. Dembitsky, Michael E. Davis & Mark A. Sussman, Dec 1 2019, In : Communications Biology. 2, 1, 205.

    Research output: Contribution to journalArticle

  14. Published

    Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease

    Karima Ait-Aissa, Scott C. Blaszak, Gisela Beutner, Shirng Wern Tsaih, Garrett Morgan, Janine H. Santos & 7 others, Michael J. Flister, David L. Joyce, Amadou K.S. Camara, David D. Gutterman, Anthony J. Donato, George A. Porter & Andreas M. Beyer, Dec 1 2019, In : Scientific reports. 9, 1, 7623.

    Research output: Contribution to journalArticle

  15. Published

    Statin-specific inhibition of Rab-GTPase regulates cPKC-mediated IKs internalization

    Elsa Ronzier, Xiaorong Xu Parks, Haani Qudsi & Coeli M. Lopes, Dec 1 2019, In : Scientific reports. 9, 1, 17747.

    Research output: Contribution to journalArticle

  16. Published

    Lysophosphatidic acid and its receptors: pharmacology and therapeutic potential in atherosclerosis and vascular disease

    Ying Zhou, Peter J. Little, Hang T. Ta, Suowen Xu & Danielle Kamato, Dec 2019, In : Pharmacology and Therapeutics. 204, 107404.

    Research output: Contribution to journalReview article

  17. Published

    Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase

    Sivareddy Kotla, Nhat Tu Le, Hang Thi Vu, Kyung Ae Ko, Young Jin Gi, Tamlyn N. Thomas & 5 others, Carolyn Giancursio, Aldos J. Lusis, John P. Cooke, Keigi Fujiwara & Jun ichi Abe, Nov 2019, In : Metabolism: clinical and experimental. 100, 153962.

    Research output: Contribution to journalArticle

  18. Published

    ORE identifies extreme expression effects enriched for rare variants

    F. Richter, G. E. Hoffman, K. B. Manheimer, N. Patel, A. J. Sharp, D. McKean & 13 others, S. U. Morton, S. Depalma, J. Gorham, A. Kitaygorodksy, G. A. Porter, A. Giardini, Y. Shen, W. K. Chung, J. G. Seidman, C. E. Seidman, E. E. Schadt, B. D. Gelb & Oliver Stegle, Oct 15 2019, In : Bioinformatics. 35, 20, p. 3906-3912 7 p.

    Research output: Contribution to journalArticle

  19. Published

    Redox Signaling through Compartmentalization of Reactive Oxygen Species: Implications for Health and Disease

    Andrew P. Wojtovich, Brandon J. Berry & Alexander Galkin, Sep 20 2019, In : Antioxidants and Redox Signaling. 31, 9, p. 591-593 3 p.

    Research output: Contribution to journalReview article

  20. Published

    Molecular mechanisms of arrhythmogenic cardiomyopathy

    Karyn M. Austin, Michael A. Trembley, Stephanie F. Chandler, Stephen P. Sanders, Jeffrey E. Saffitz, Dominic J. Abrams & 1 others, William T. Pu, Sep 1 2019, In : Nature Reviews Cardiology. 16, 9, p. 519-537 19 p.

    Research output: Contribution to journalReview article

  21. Published

    hnRNP L-mediated RNA switches function as a hypoxia-induced translational regulon

    Kadiam C. Venkata Subbaiah, Jiangbin Wu, Alka Potdar & Peng Yao, Aug 27 2019, In : Biochemical and Biophysical Research Communications. 516, 3, p. 753-759 7 p.

    Research output: Contribution to journalArticle

  22. Published

    Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

    Robert C. Wirka, Dhananjay Wagh, David T. Paik, Milos Pjanic, Trieu Nguyen, Clint L. Miller & 15 others, Ramen Kundu, Manabu Nagao, John Coller, Tiffany K. Koyano, Robyn Fong, Y. Joseph Woo, Boxiang Liu, Stephen B. Montgomery, Joseph C. Wu, Kuixi Zhu, Rui Chang, Melissa Alamprese, Michelle D. Tallquist, Juyong B. Kim & Thomas Quertermous, Aug 1 2019, In : Nature medicine. 25, 8, p. 1280-1289 10 p.

    Research output: Contribution to journalArticle

  23. Published

    Mos1 element-mediated CRISPR integration of transgenes in Caenorhabditis elegans

    Nicholas S. Philip, Fernando Escobedo, Laura L. Bahr, Brandon J. Berry & Andrew P. Wojtovich, Aug 1 2019, In : G3: Genes, Genomes, Genetics. 9, 8, p. 2629-2635 7 p.

    Research output: Contribution to journalArticle

  24. Published

    Iron and Atherosclerosis: The Link Revisited

    Suowen Xu, Aug 2019, In : Trends in Molecular Medicine. 25, 8, p. 659-661 3 p.

    Research output: Contribution to journalShort survey

  25. Published

    Physiologic implications of reactive oxygen species production by mitochondrial complex I reverse electron transport

    John O. Onukwufor, Brandon J. Berry & Andrew P. Wojtovich, Aug 2019, In : Antioxidants. 8, 8, 285.

    Research output: Contribution to journalReview article

  26. Published

    The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis

    Suowen Xu, Yanni Xu, Peng Liu, Shuya Zhang, Huan Liu, Spencer Slavin & 10 others, Sandeep Kumar, Marina Koroleva, Jinque Luo, Xiaoqian Wu, Arshad Rahman, Jaroslav Pelisek, Hanjoong Jo, Shuyi Si, Clint L. Miller & Zheng Gen Jin, Aug 2019, In : European heart journal. 40, 29, p. 2398-2408 11 p.

    Research output: Contribution to journalArticle

  27. Published

    Hutchinson–Gilford Progeria Syndrome: Cardiovascular Pathologies and Potential Therapies

    Suowen Xu & Zheng Gen Jin, Jul 2019, In : Trends in Biochemical Sciences. 44, 7, p. 561-564 4 p.

    Research output: Contribution to journalShort survey

  28. Published

    Protective transcriptional mechanisms in cardiomyocytes and cardiac fibroblasts

    Cameron S. Brand, Janet K. Lighthouse & Michael A. Trembley, Jul 2019, In : Journal of Molecular and Cellular Cardiology. 132, p. 1-12 12 p.

    Research output: Contribution to journalReview article

  29. Published

    Myofibroblast-specific YY1 promotes liver fibrosis

    Huan Liu, Shuya Zhang, Suowen Xu, Marina Koroleva, Eric M. Small & Zheng Gen Jin, Jun 30 2019, In : Biochemical and Biophysical Research Communications. 514, 3, p. 913-918 6 p.

    Research output: Contribution to journalArticle

  30. Published

    The post-cardiac arrest syndrome: A case for lung–brain coupling and opportunities for neuroprotection

    Nguyen Mai, Kathleen Miller-Rhodes, Sara Knowlden & Marc W. Halterman, Jun 1 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 6, p. 939-958 20 p.

    Research output: Contribution to journalReview article

  31. Published

    Lung-Derived SOD3 Attenuates Neurovascular Injury After Transient Global Cerebral Ischemia

    Nguyen Mai, Kathleen Miller-Rhodes, Viollandi Prifti, Minsoo Kim, Michael A. O'Reilly & Marc W. Halterman, May 7 2019, In : Journal of the American Heart Association. 8, 9, e011801.

    Research output: Contribution to journalArticle

  32. Published

    TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression

    Quanyi Zhao, Robert Wirka, Trieu Nguyen, Manabu Nagao, Paul Cheng, Clint L. Miller & 3 others, Juyong Brian Kim, Milos Pjanic & Thomas Quertermous, May 2 2019, In : Genome medicine. 11, 1, 23.

    Research output: Contribution to journalArticle

  33. Published

    Acetylcholine inhibits platelet activation

    John A. Bennett, Sara K. Ture, Rachel A. Schmidt, Michael A. Mastrangelo, Scott J. Cameron, Lara E. Terry & 3 others, David I. Yule, Craig N. Morrell & Charles J. Lowenstein, May 2019, In : Journal of Pharmacology and Experimental Therapeutics. 369, 2, p. 182-187 6 p.

    Research output: Contribution to journalArticle

  34. Published

    Targeting LOX-1 in atherosclerosis and vasculopathy: current knowledge and future perspectives

    Kunming Tian, Sayoko Ogura, Peter J. Little, Suo wen Xu & Tatsuya Sawamura, May 2019, In : Annals of the New York Academy of Sciences. 1443, 1, p. 34-53 20 p.

    Research output: Contribution to journalReview article

  35. Published

    The Platelet Napoleon Complex-Small Cells, but Big Immune Regulatory Functions

    Craig N. Morrell, Daphne N. Pariser, Zachary T. Hilt & Denisse Vega Ocasio, Apr 26 2019, In : Annual Review of Immunology. 37, p. 125-144 20 p.

    Research output: Contribution to journalArticle

  36. Published

    MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis

    Jun ichi Abe, Kyung Ae Ko, Sivareddy Kotla, Yin Wang, Jesus Paez-Mayorga, Ik Jae Shin & 20 others, Masaki Imanishi, Hang Thi Vu, Yunting Tao, Miguel M. Leiva-Juarez, Tamlyn N. Thomas, Jan L. Medina, Jong Hak Won, Yuka Fujii, Carolyn J. Giancursio, Elena McBeath, Ji Hyun Shin, Liliana Guzman, Rei J. Abe, Jack Taunton, Naoki Mochizuki, William Faubion, John P. Cooke, Keigi Fujiwara, Scott E. Evans & Nhat Tu Le, Apr 4 2019, In : JCI Insight. 4, 7, e125570.

    Research output: Contribution to journalArticle

  37. Published

    LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II

    Young Min Hyun, Young Ho Choe, Sang A. Park & Minsoo Kim, Apr 1 2019, In : Experimental and Molecular Medicine. 51, 4, 39.

    Research output: Contribution to journalArticle

  38. Published

    Sacubitril/Valsartan Decreases Cardiac Fibrosis in Left Ventricle Pressure Overload by Restoring PKG Signaling in Cardiac Fibroblasts

    Ryan M. Burke, Janet K. Lighthouse, Deanne M. Mickelsen & Eric M. Small, Apr 1 2019, In : Circulation: Heart Failure. 12, 4, e005565.

    Research output: Contribution to journalArticle

  39. Published

    Fluvastatin inhibits Rab5-mediated IKs internalization caused by chronic Ca 2+ -dependent PKC activation

    Xiaorong Xu Parks, Elsa Ronzier, Jin O-Uchi & Coeli M. Lopes, Apr 2019, In : Journal of Molecular and Cellular Cardiology. 129, p. 314-325 12 p.

    Research output: Contribution to journalArticle

  40. Published

    Phosphorylation of Hsp20 Promotes Fibrotic Remodeling and Heart Failure

    George T. Gardner, Joshua G. Travers, Jiang Qian, Guan Sheng Liu, Kobra Haghighi, Nathan Robbins & 6 others, Min Jiang, Yutian Li, Guo Chang Fan, Jack Rubinstein, Burns C. Blaxall & Evangelia G. Kranias, Apr 2019, In : JACC: Basic to Translational Science. 4, 2, p. 188-199 12 p.

    Research output: Contribution to journalArticle

  41. Published

    Pre-existing fibroblasts of epicardial origin are the primary source of pathological fibrosis in cardiac ischemia and aging

    Pearl Quijada, Adwiteeya Misra, Lissette S. Velasquez, Ryan M. Burke, Janet K. Lighthouse, Deanne M. Mickelsen & 2 others, Ronald A. Dirkx & Eric M. Small, Apr 2019, In : Journal of Molecular and Cellular Cardiology. 129, p. 92-104 13 p.

    Research output: Contribution to journalArticle

  42. Published

    Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics

    Suowen Xu, Danielle Kamato, Peter J. Little, Shinichi Nakagawa, Jaroslav Pelisek & Zheng Gen Jin, Apr 2019, In : Pharmacology and Therapeutics. 196, p. 15-43 29 p.

    Research output: Contribution to journalReview article

  43. Published

    Targeting Mechanosensitive Transcription Factors in Atherosclerosis

    Niu Niu, Suowen Xu, Yanni Xu, Peter J. Little & Zheng Gen Jin, Apr 2019, In : Trends in pharmacological sciences. 40, 4, p. 253-266 14 p.

    Research output: Contribution to journalReview article

  44. Published

    Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation

    Wen Wu, Wei Zhang, Mihyun Choi, Jinjing Zhao, Ping Gao, Min Xue & 3 others, Harold A. Singer, David Jourd'heuil & Xiaochun Long, Apr 2019, In : Redox Biology. 22, 101137.

    Research output: Contribution to journalArticle

  45. Published

    Meal for two: Human cytomegalovirus-induced activation of cellular metabolism

    Irene Rodríguez-Sánchez & Joshua Munger, Mar 19 2019, In : Viruses. 11, 3, 273.

    Research output: Contribution to journalReview article

  46. Published

    Platelet-derived β2M regulates monocyte inflammatory responses

    Zachary T. Hilt, Daphne N. Pariser, Sara K. Ture, Amy Mohan, Pearl Quijada, Akua A. Asante & 10 others, Scott J. Cameron, Julie A. Sterling, Alyssa R. Merkel, Andrew L. Johanson, Jermaine L. Jenkins, Eric M. Small, Kathleen E. McGrath, James Palis, Michael R. Elliott & Craig N. Morrell, Mar 7 2019, In : JCI Insight. 4, 5

    Research output: Contribution to journalArticle

  47. Published

    Activated human lung fibroblasts produce extracellular vesicles with antifibrotic prostaglandins

    Shannon H. Lacy, Collynn F. Woeller, Thomas H. Thatcher, Stephen J. Pollock, Eric M. Small, Patricia J. Sime & 1 others, Richard P. Phipps, Mar 2019, In : American journal of respiratory cell and molecular biology. 60, 3, p. 269-278 10 p.

    Research output: Contribution to journalArticle

  48. Published

    CRISPR links to long noncoding RNA function in mice: A practical approach

    Joseph M. Miano, Xiaochun Long & Qing Lyu, Mar 2019, In : Vascular pharmacology. 114, p. 1-12 12 p.

    Research output: Contribution to journalReview article

  49. Published

    Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals: Implications for Atherogenesis

    Meera V. Singh, Sivareddy Kotla, Nhat Tu Le, Kyung Ae Ko, Kyung Sun Heo, Yin Wang & 21 others, Yuka Fujii, Hang Thi Vu, Elena McBeath, Tamlyn N. Thomas, Young Jin Gi, Yunting Tao, Jan L. Medina, Jack Taunton, Nancy Carson, Vikram Dogra, Marvin M. Doyley, Alicia Tyrell, Wang Lu, Xing Qiu, Nicole E. Stirpe, Kathleen J. Gates, Christine Hurley, Keigi Fujiwara, Sanjay B. Maggirwar, Giovanni Schifitto & Jun Ichi Abe, Feb 26 2019, In : Circulation. 139, 9, p. 1199-1216 18 p.

    Research output: Contribution to journalArticle

  50. Published

    Human antigen R as a therapeutic target in pathological cardiac hypertrophy

    Lisa C. Green, Sarah R. Anthony, Samuel Slone, Lindsey Lanzillotta, Michelle L. Nieman, Xiaoqing Wu & 11 others, Nathan Robbins, Shannon M. Jones, Sudeshna Roy, A. Phillip Owens, Jeffrey Aube, Liang Xu, John N. Lorenz, Burns C. Blaxall, Jack Rubinstein, Joshua B. Benoit & Michael Tranter, Feb 21 2019, In : JCI Insight. 4, 4

    Research output: Contribution to journalArticle

  51. Published

    Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and Von Willebrand Factor Plasma Levels

    Maria Sabater-Lleal, Jennifer E. Huffman, Paul S. De Vries, Jonathan Marten, Michael A. Mastrangelo, Ci Song & 70 others, Nathan Pankratz, Cavin K. Ward-Caviness, Lisa R. Yanek, Stella Trompet, Graciela E. Delgado, Xiuqing Guo, Traci M. Bartz, Angel Martinez-Perez, Marine Germain, Hugoline G. De Haan, Ayse B. Ozel, Ozren Polasek, Albert V. Smith, John D. Eicher, Alex P. Reiner, Weihong Tang, Neil M. Davies, David J. Stott, Jerome I. Rotter, Geoffrey H. Tofler, Eric Boerwinkle, Moniek P.M. De Maat, Marcus E. Kleber, Paul Welsh, Jennifer A. Brody, Ming Huei Chen, Dhananjay Vaidya, José Manuel Soria, Pierre Suchon, Astrid Van Hylckama Vlieg, Karl C. Desch, Ivana Kolcic, Peter K. Joshi, Lenore J. Launer, Tamara B. Harris, Harry Campbell, Igor Rudan, Diane M. Becker, Jun Z. Li, Fernando Rivadeneira, André G. Uitterlinden, Albert Hofman, Oscar H. Franco, Mary Cushman, Bruce M. Psaty, Pierre Emmanuel Morange, Barbara Mcknight, Michael R. Chong, Israel Fernandez-Cadenas, Jonathan Rosand, Arne Lindgren, Vilmundur Gudnason, James F. Wilson, Caroline Hayward, David Ginsburg, Myriam Fornage, Frits R. Rosendaal, Juan Carlos Souto, Lewis C. Becker, Nancy S. Jenny, Winfried März, J. Wouter Jukema, Abbas Dehghan, David Alexandre Trégouët, Alanna C. Morrison, Andrew D. Johnson, Christopher J. O'donnell, David P. Strachan, Charles J. Lowenstein & Nicholas L. Smith, Jan 29 2019, In : Circulation. 139, 5, p. 620-635 16 p.

    Research output: Contribution to journalArticle

  52. Published

    Exercise promotes a cardioprotective gene program in resident cardiac fibroblasts

    Janet K. Lighthouse, Ryan M. Burke, Lissette S. Velasquez, Ronald A. Dirkx, Alessandro Aiezza, Christine S. Moravec & 3 others, Jeffrey D. Alexis, Alex Rosenberg & Eric M. Small, Jan 10 2019, In : JCI Insight. 4, 1, e92098.

    Research output: Contribution to journalArticle

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