University of Toledo Health Science Campus

City Toledo
State Ohio
  1. 2020
  2. Published

    Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia

    Shungang Zhang, Joshua D. Breidenbach, Fatimah K. Khalaf, Prabhatchandra R. Dube, Chrysan J. Mohammed, Apurva Lad & 9 others, Stanislaw Stepkowski, Terry D. Hinds, Sivarajan Kumarasamy, Andrew Kleinhenz, Jiang Tian, Deepak Malhotra, David J. Kennedy, Christopher J. Cooper & Steven T. Haller, Apr 7 2020, In : Journal of the American Heart Association. 9, 7, p. e014072

    Research output: Contribution to journalArticle

  3. Published

    Epithelial and Endothelial Adhesion of Immune Cells Is Enhanced by Cardiotonic Steroid Signaling Through Na+/K+-ATPase-α-1

    Fatimah K. Khalaf, Iman Tassavvor, Amal Mohamed, Yiliang Chen, Deepak Malhotra, Zijian Xie & 5 others, Jiang Tian, Steven T. Haller, Kristen Westfall, W. H.Wilson Tang & David J. Kennedy, Feb 4 2020, In : Journal of the American Heart Association. 9, 3, e013933.

    Research output: Contribution to journalArticle

  4. Published

    Microbiota are critical for vascular physiology: Germ-free status weakens contractility and induces sex-specific vascular remodeling in mice

    Jonnelle M. Edwards, Shaunak Roy, Jeremy C. Tomcho, Zachary J. Schreckenberger, Saroj Chakraborty, Nicole R. Bearss & 5 others, Piu Saha, Cameron G. McCarthy, Matam Vijay-Kumar, Bina Joe & Camilla F. Wenceslau, Feb 1 2020, In : Vascular Pharmacology. 125-126, 106633.

    Research output: Contribution to journalArticle

  5. Published

    Mechanism and biomarkers in aortitis––a review

    Benjamin Benhuri, Ammar ELJack, Bashar Kahaleh & Ritu Chakravarti, Jan 1 2020, In : Journal of Molecular Medicine. 98, 1, p. 11-23 13 p.

    Research output: Contribution to journalReview article

  6. Published

    The role of cofilin in age-related neuroinflammation

    Amsha S. Alsegiani & Zahoor A. Shah, Jan 1 2020, In : Neural Regeneration Research. 15, 8, p. 1451-1459 9 p.

    Research output: Contribution to journalReview article

  7. 2019
  8. Published

    TRPM8 channel activation triggers relaxation of pudendal artery with increased sensitivity in the hypertensive rats

    Darizy Flavia Silva, Camilla Ferreira Wenceslau, Cameron G. Mccarthy, Theodora Szasz, S. Ogbi & R. Clinton Webb, Sep 2019, In : Pharmacological Research. 147, 104329.

    Research output: Contribution to journalArticle

  9. Published

    Regulated endocrine-specific protein-18, an emerging endocrine protein in physiology: A literature review

    Ealla Atari, Mitchel C. Perry, Pedro A. Jose & Sivarajan Kumarasamy, Jul 11 2019, In : Endocrinology. 160, 9, p. 2093-2100 8 p.

    Research output: Contribution to journalArticle

  10. Published

    Proinflammatory Effects of Cardiotonic Steroids Mediated by NKA α-1 (Na+/K+-ATPase α-1)/Src Complex in Renal Epithelial Cells and Immune Cells

    Fatimah K. Khalaf, Prabhatchandra Dube, Andrew L. Kleinhenz, Deepak Malhotra, Amira Gohara, Christopher A. Drummond & 4 others, Jiang Tian, Steven T. Haller, Zijian Xie & David J. Kennedy, Jul 1 2019, In : Hypertension. 74, 1, p. 73-82 10 p.

    Research output: Contribution to journalArticle

  11. Published

    Early Rapid Decline in Kidney Function in Medically Managed Patients With Atherosclerotic Renal Artery Stenosis

    Emily L. Cooper, Yanmei Xie, Hanh Nguyen, Pamela S. Brewster, Haden Sholl, Megan Sharrett & 13 others, Kaili Ren, Tian Chen, Katherine R. Tuttle, Steven T. Haller, Kenneth Jamerson, Timothy P. Murphy, Ralph B. D'Agostino, Joseph M. Massaro, William Henrich, Christopher J. Cooper, Donald E. Cutlip, Lance D. Dworkin & Joseph I. Shapiro, Jun 4 2019, In : Journal of the American Heart Association. 8, 11, e012366.

    Research output: Contribution to journalArticle

  12. Published

    TRAF6 Plays a Proviral Role in Tick-Borne Flavivirus Infection through Interaction with the NS3 Protease

    Brian H. Youseff, Thomas G. Brewer, Kristin L. McNally, Adaeze O. Izuogu, Kirk J. Lubick, John B. Presloid & 5 others, Saad Alqahtani, Saurabh Chattopadhyay, Sonja M. Best, Xiche Hu & R. Travis Taylor, May 31 2019, In : iScience. 15, p. 489-501 13 p.

    Research output: Contribution to journalArticle

  13. Published

    The non-transcriptional activity of IRF3 modulates hepatic immune cell populations in acute-on-chronic ethanol administration in mice

    Carlos Sanz-Garcia, Kyle L. Poulsen, Damien Bellos, Han Wang, Megan R. McMullen, Xiaoxia Li & 3 others, Saurabh Chattopadhyay, Ganes Sen & Laura E. Nagy, May 2019, In : Journal of Hepatology. 70, 5, p. 974-984 11 p.

    Research output: Contribution to journalArticle

  14. Published

    Paying the toll for inflammation: Immunoreceptor-mediated vascular dysfunction in hypertension

    Cameron G. McCarthy, Styliani Goulopoulou & R. Clinton Webb, Mar 1 2019, In : Hypertension. 73, 3, p. 514-521 8 p.

    Research output: Contribution to journalArticle

  15. Published

    B lymphoma moloney murine leukemia virus insertion region 1 homolog: The janus-faced polycomb protein that will break your heart

    Cameron G. McCarthy, Camilla Ferreira Wenceslau & Bina Joe, Feb 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 2, p. H257-H259

    Research output: Contribution to journalComment/debate

  16. Published

    Editorial: Trauma-induced, DAMP-mediated remote organ injury, and immunosuppression in the acutely Ill patient

    Julien Pottecher, Alain Meyer, Camilla Ferreira Wenceslau, Kim Timmermans, Carl Jeffrey Hauser & Walter Gottlieb Land, Jan 1 2019, In : Frontiers in Immunology. 10, AUG, 1971.

    Research output: Contribution to journalEditorial

  17. Published

    Interleukin 21 (IL-21) regulates chronic allograft vasculopathy (CAV) in murine heart allograft rejection

    Mithun Khattar, Caitlin E. Baum, Paul Schroder, Joshua D. Breidenbach, Steven T. Haller, Wenhao Chen & 1 others, Stanislaw Stepkowski, Jan 1 2019, In : PloS one. 14, 11, e0225624.

    Research output: Contribution to journalArticle

  18. Published

    Novel contributors and mechanisms of cellular senescence in hypertension-associated premature vascular aging

    Cameron G. McCarthy, Camilla F. Wenceslau, R. Clinton Webb & Bina Joe, Jan 1 2019, In : American journal of hypertension. 32, 8, p. 709-719 11 p.

    Research output: Contribution to journalReview article

  19. Published

    Reconstitution of autophagy ameliorates vascular function and arterial stiffening in spontaneously hypertensive rats

    Cameron G. McCarthy, Camilla F. Wenceslau, Fabiano B. Calmasini, Nicole S. Klee, Michael W. Brands, Bina Joe & 1 others, R. Clinton Webb, Jan 1 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 317, 5, p. H1013-H1027

    Research output: Contribution to journalArticle

  20. Published

    Targeting endothelial barrier dysfunction caused by circulating bacterial and mitochondrial n-formyl peptides with deformylase

    Patricia Martinez-Quinones, Amel Komic, Cameron G. McCarthy, R. Clinton Webb & Camilla Ferreira Wenceslau, Jan 1 2019, In : Frontiers in Immunology. 10, JUN, 1270.

    Research output: Contribution to journalArticle

  21. 2018
  22. Published

    Cofilin Knockdown Attenuates Hemorrhagic Brain Injury-induced Oxidative Stress and Microglial Activation in Mice

    Qasim Alhadidi, Kevin M. Nash, Saleh Alaqel, Muhammad Shahdaat Bin Sayeed & Zahoor A. Shah, Jul 15 2018, In : Neuroscience. 383, p. 33-45 13 p.

    Research output: Contribution to journalArticle

  23. Published

    Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice

    Laura E. Crotty Alexander, Christopher A. Drummond, Mark Hepokoski, Denzil Mathew, Alex Moshensky, Andrew Willeford & 11 others, Soumita Das, Prabhleen Singh, Zach Yong, Jasmine H. Lee, Kevin Vega, Ashley Du, John Shin, Christian Javier, Jiang Tian, Joan Heller Brown & Ellen C. Breen, Jun 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 314, 6, p. R834-R847

    Research output: Contribution to journalArticle

  24. Published

    Targeted disruption of regulated endocrine-specific protein ( Resp18) in Dahl SS/Mcw rats aggravates salt-induced hypertension and renal injury

    Sivarajan Kumarasamy, Harshal Waghulde, Xi Cheng, Steven T. Haller, Blair Mell, Basrur Abhijith & 3 others, Usman M. Ashraf, Ealla Atari & Bina Joe, May 1 2018, In : Physiological genomics. 50, 5, p. 369-375 7 p.

    Research output: Contribution to journalArticle

  25. Published

    Na/K-ATPase signaling mediates miR-29b-3p regulation and cardiac fibrosis formation in mice with chronic kidney disease

    Christopher A. Drummond, Xiaoming Fan, Steven T. Haller, David J. Kennedy, Jiang Liu & Jiang Tian, May 2018, In : PloS one. 13, 5, e0197688.

    Research output: Contribution to journalArticle

  26. Published

    Constitutively bound EGFR–mediated tyrosine phosphorylation of TLR9 is required for its ability to signal

    Manoj Veleeparambil, Darshana Poddar, Samar Abdulkhalek, Patricia M. Kessler, Michifumi Yamashita, Saurabh Chattopadhyay & 1 others, Ganes C. Sen, Apr 15 2018, In : Journal of Immunology. 200, 8, p. 2809-2818 10 p.

    Research output: Contribution to journalArticle

  27. Published

    Toll-like receptor 9–dependent AMPKa activation occurs via TAK1 and contributes to RhoA/ROCK signaling and actin polymerization in vascular smooth muscle cells

    Cameron G. McCarthy, Camilla F. Wenceslau, Safia Ogbi, Theodora Szasz & R. Clinton Webb, Apr 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 1, p. 60-71 12 p.

    Research output: Contribution to journalArticle

  28. Published

    Liver-specific rescuing of CEACAM1 reverses endothelial and cardiovascular abnormalities in male mice with null deletion of Ceacam1 gene

    Lucia Russo, Harrison T. Muturi, Hilda E. Ghadieh, Alexander M. Wisniewski, Eric E. Morgan, Syed S. Quadri & 6 others, Gavin P. Landesberg, Helmy M. Siragy, Guillermo Vazquez, Rosario Scalia, Rajesh Gupta & Sonia M. Najjar, Mar 2018, In : Molecular Metabolism. 9, p. 98-113 16 p.

    Research output: Contribution to journalArticle

  29. Published

    Cofilin Mediates LPS-Induced Microglial Cell Activation and Associated Neurotoxicity Through Activation of NF-κB and JAK–STAT Pathway

    Qasim Alhadidi & Zahoor A. Shah, Feb 1 2018, In : Molecular Neurobiology. 55, 2, p. 1676-1691 16 p.

    Research output: Contribution to journalArticle

  30. Published

    Development of a reactive oxygen species-sensitive nitric oxide synthase inhibitor for the treatment of ischemic stroke

    Kevin M. Nash, Isaac T. Schiefer & Zahoor A. Shah, Feb 1 2018, In : Free Radical Biology and Medicine. 115, p. 395-404 10 p.

    Research output: Contribution to journalArticle

  31. Published

    Properdin

    Viviana P. Ferreira, Jan 1 2018, The Complement FactsBook: Second Edition. Elsevier, p. 283-293 11 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  32. Published

    A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

    Gayatri Subramanian, Teodora Kuzmanovic, Ying Zhang, Cara Beate Peter, Manoj Veleeparambil, Ritu Chakravarti & 2 others, Ganes C. Sen & Saurabh Chattopadhyay, Jan 2018, In : PLoS pathogens. 14, 1, e1006877.

    Research output: Contribution to journalArticle

  33. 2017
  34. Published

    Alcohol consumption impairs the ependymal cilia motility in the brain ventricles

    Alzahra J.Al Omran, Hannah C. Saternos, Yusuf S. Althobaiti, Alexander Wisner, Youssef Sari, Surya M. Nauli & 1 others, Wissam A. Aboualaiwi, Dec 1 2017, In : Scientific reports. 7, 1, 13652.

    Research output: Contribution to journalArticle

  35. Published

    Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice

    Lucia Russo, Harrison T. Muturi, Hilda E. Ghadieh, Simona S. Ghanem, Thomas A. Bowman, Hye Lim Noh & 5 others, Sezin Dagdeviren, Godwin Y. Dogbey, Jason K. Kim, Garrett Heinrich & Sonia M. Najjar, Dec 1 2017, In : Diabetologia. 60, 12, p. 2463-2474 12 p.

    Research output: Contribution to journalArticle

  36. Published

    Peritoneal cavity lavage reduces the presence of mitochondrial damage associated molecular patterns in open abdomen patients

    Patricia A. Martinez-Quinones, Cameron G. McCarthy, Caleb J. Mentzer, Camilla F. Wenceslau, Steven B. Holsten, R. Clinton Webb & 1 others, Keith O'Malley, Dec 1 2017, In : Journal of Trauma and Acute Care Surgery. 83, 6, p. 1062-1065 4 p.

    Research output: Contribution to journalArticle

  37. Published

    Structural basis for the broad substrate specificity of the human tyrosylprotein sulfotransferase-1

    Shinnosuke Tanaka, Toshiaki Nishiyori, Hidetaka Kojo, Reo Otsubo, Moe Tsuruta, Katsuhisa Kurogi & 4 others, Ming Cheh Liu, Masahito Suiko, Yoichi Sakakibara & Yoshimitsu Kakuta, Dec 1 2017, In : Scientific reports. 7, 1, 8776.

    Research output: Contribution to journalArticle

  38. Published

    Effect of myostatin deletion on cardiac and microvascular function

    Joshua T. Butcher, M. Irfan Ali, Merry W. Ma, Cameron G. McCarthy, Bianca N. Islam, Lauren G. Fox & 4 others, James D. Mintz, Sebastian Larion, David J. Fulton & David W. Stepp, Dec 2017, In : Physiological reports. 5, 23, e13525.

    Research output: Contribution to journalArticle

  39. Published

    Factor H C-terminal domains are critical for regulation of platelet/granulocyte aggregate formation

    Adam Z. Blatt, Gurpanna Saggu, Claudio Cortes, Andrew P. Herbert, David Kavanagh, Daniel Ricklin & 2 others, John D. Lambris & Viviana P. Ferreira, Nov 23 2017, In : Frontiers in Immunology. 8, NOV, 1586.

    Research output: Contribution to journalArticle

  40. Published

    MicroRNA profiling in kidney disease: Plasma versus plasma-derived exosomes

    Jeffrey X. Xie, Xiaoming Fan, Christopher A. Drummond, Reetam Majumder, Yanmei Xie, Tian Chen & 6 others, Lijun Liu, Steven T. Haller, Pamela S. Brewster, Lance D. Dworkin, Christopher J. Cooper & Jiang Tian, Sep 5 2017, In : Gene. 627, p. 1-8 8 p.

    Research output: Contribution to journalArticle

  41. Published

    RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

    Saurabh Chattopadhyay & Ganes C. Sen, Mar 1 2017, In : Protein and Cell. 8, 3, p. 165-168 4 p.

    Research output: Contribution to journalReview article

  42. Published

    Cigarette smoking and cardio-renal events in patients with atherosclerotic renal artery stenosis

    Christopher A. Drummond, Pamela S. Brewster, Wencan He, Kaili Ren, Yanmei Xie, Katherine R. Tuttle & 10 others, Steven T. Haller, Kenneth Jamerson, Lance D. Dworkin, Donald E. Cutlip, Timothy P. Murphy, Ralph B. D'Agostino, William L. Henrich, Jiang Tian, Joseph I. Shapiro & Christopher J. Cooper, Mar 2017, In : PloS one. 12, 3, e0173562.

    Research output: Contribution to journalArticle

  43. Published

    Chloroquine Suppresses the Development of Hypertension in Spontaneously Hypertensive Rats

    Cameron G. McCarthy, Camilla F. Wenceslau, Styliani Goulopoulou, Babak Baban, Takayuki Matsumoto & R. Clinton Webb, Feb 1 2017, In : American journal of hypertension. 30, 2, p. 173-181 9 p.

    Research output: Contribution to journalArticle

  44. Published

    Targeted disruption of Cd40 in a genetically hypertensive rat model attenuates renal fibrosis and proteinuria, independent of blood pressure

    Steven T. Haller, Sivarajan Kumarasamy, David A. Folt, Leah M. Wuescher, Stanislaw Stepkowski, Manish Karamchandani & 12 others, Harshal Waghulde, Blair Mell, Muhammad Chaudhry, Kyle Maxwell, Siddhi Upadhyaya, Christopher A. Drummond, Jiang Tian, Wanda E. Filipiak, Thomas L. Saunders, Joseph I. Shapiro, Bina Joe & Christopher J. Cooper, Feb 1 2017, In : Kidney international. 91, 2, p. 365-374 10 p.

    Research output: Contribution to journalArticle

  45. Published

    Deep Transcriptomic Profiling of M1 Macrophages Lacking Trpc3

    Sivarajan Kumarasamy, Sumeet Solanki, Oluwatomisin T. Atolagbe, Bina Joe, Lutz Birnbaumer & Guillermo Vazquez, Jan 4 2017, In : Scientific reports. 7, 39867.

    Research output: Contribution to journalArticle

  46. 2016
  47. Published

    Cigarette smoking causes epigenetic changes associated with cardiorenal fibrosis

    Christopher A. Drummond, Laura E. Crotty Alexander, Steven T. Haller, Xiaoming Fan, Jeffrey X. Xie, David J. Kennedy & 7 others, Jiang Liu, Yanling Yan, Dawn Alita Hernandez, Denzil P. Mathew, Christopher J. Cooper, Joseph I. Shapiro & Jiang Tian, Dec 19 2016, In : Physiological genomics. 48, 12, p. 950-960 11 p.

    Research output: Contribution to journalArticle

  48. Published

    The Borrelia burgdorferi CheY3 response regulator is essential for chemotaxis and completion of its natural infection cycle

    Elizabeth A. Novak, Padmapriya Sekar, Hui Xu, Ki Hwan Moon, Akarsh Manne, R. Mark Wooten & 1 others, M. D.A. Motaleb, Dec 1 2016, In : Cellular Microbiology. 18, 12, p. 1782-1799 18 p.

    Research output: Contribution to journalArticle

  49. Published

    Toll-like receptor 4 activation contributes to diabetic bladder dysfunction in a murine model of type 1 diabetes

    Theodora Szasz, Camilla F. Wenceslau, Beth Burgess, Kenia P. Nunes & R. Clinton Webb, Dec 1 2016, In : Diabetes. 65, 12, p. 3754-3764 11 p.

    Research output: Contribution to journalArticle

  50. Published

    Fenofibrate decreases insulin clearance and insulin secretion to maintain insulin sensitivity

    Sadeesh K. Ramakrishnan, Lucia Russo, Simona S. Ghanem, Payal R. Patel, Ana Maria Oyarce, Garrett Heinrich & 1 others, Sonia M. Najjar, Nov 11 2016, In : Journal of Biological Chemistry. 291, 46, p. 23915-23924 10 p.

    Research output: Contribution to journalArticle

  51. Published

    Autoimmune therapeutic chloroquine lowers blood pressure and improves endothelial function in spontaneously hypertensive rats

    Cameron G. McCarthy, Camilla F. Wenceslau, Styliani Goulopoulou, Safia Ogbi, Takayuki Matsumoto & R. Clinton Webb, Nov 1 2016, In : Pharmacological Research. 113, p. 384-394 11 p.

    Research output: Contribution to journalArticle

  52. Published

    Properdin: a tightly regulated critical inflammatory modulator

    Adam Z. Blatt, Sabina Pathan & Viviana P. Ferreira, Nov 1 2016, In : Immunological Reviews. 274, 1, p. 172-190 19 p.

    Research output: Contribution to journalReview article

  53. Published

    Rapamycin attenuates cardiac fibrosis in experimental uremic cardiomyopathy by reducing marinobufagenin levels and inhibiting downstream pro-fibrotic signaling

    Steven T. Haller, Yanling Yan, Christopher A. Drummond, Joe Xie, Jiang Tian, David J. Kennedy & 8 others, Victoria Y. Shilova, Zijian Xie, Jiang Liu, Christopher J. Cooper, Deepak Malhotra, Joseph I. Shapiro, Olga V. Fedorova & Alexei Y. Bagrov, Oct 1 2016, In : Journal of the American Heart Association. 5, 10, e004106.

    Research output: Contribution to journalArticle

  54. Published

    Regulation of cardiac remodeling by cardiac Na+/K+-ATPase isoforms

    Lijun Liu, Jian Wu & David J. Kennedy, Sep 9 2016, In : Frontiers in Physiology. 7, SEP, 382.

    Research output: Contribution to journalReview article

  55. Published

    Protein Carbonylation of an Amino Acid Residue of the Na/K-ATPase α1 Subunit Determines Na/K-ATPase Signaling and Sodium Transport in Renal Proximal Tubular Cells

    Yanling Yan, Anna P. Shapiro, Brahma R. Mopidevi, Muhammad A. Chaudhry, Kyle Maxwell, Steven T. Haller & 7 others, Christopher A. Drummond, David J. Kennedy, Jiang Tian, Deepak Malhotra, Zi jian Xie, Joseph I. Shapiro & Jiang Liu, Sep 2016, In : Journal of the American Heart Association. 5, 9, e003675.

    Research output: Contribution to journalArticle

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