Xavier University of Louisiana, New Orleans

City New Orleans
State Louisiana
  1. 2019
  2. Published

    The in vitro effects of pentamidine isethionate on coagulation and fibrinolysis

    Rami A. Al-Horani, Daytriona Clemons & Madhusoodanan Mottamal, Jun 6 2019, In : Molecules. 24, 11, 2146.

    Research output: Contribution to journalArticle

  3. 2018
  4. Published

    Recent advances in the discovery and development of factor XI/XIa inhibitors

    Rami A. Al-Horani & Daniel K. Afosah, Nov 2018, In : Medicinal Research Reviews. 38, 6, p. 1974-2023 50 p.

    Research output: Contribution to journalReview article

  5. Published

    A small group of sulfated benzofurans induces steady-state submaximal inhibition of thrombin

    Daniel K. Afosah, Stephen Verespy, Rami A. Al-Horani, Rio S. Boothello, Rajesh Karuturi & Umesh R. Desai, Apr 1 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 6, p. 1101-1105 5 p.

    Research output: Contribution to journalArticle

  6. 2017
  7. Published

    Discovery of chromen-7-yl furan-2-carboxylate as a potent and selective factor XIa inhibitor

    Ahmad J. Obaidullah & Rami A. Al-Horani, Apr 1 2017, In : Cardiovascular and Hematological Agents in Medicinal Chemistry. 15, 1, p. 40-48 9 p.

    Research output: Contribution to journalArticle

  8. 2016
  9. Published

    Allosteric inhibition of factor xiiia. non-saccharide glycosaminoglycan mimetics, but not glycosaminoglycans, exhibit promising inhibition profile

    Rami A. Al-Horani, Rajesh Karuturi, Michael Lee, Daniel K. Afosah & Umesh R. Desai, Jul 2016, In : PloS one. 11, 7, e0160189.

    Research output: Contribution to journalArticle

  10. Published

    Factor XIa inhibitors: A review of the patent literature

    Rami A. Al-Horani & Umesh R. Desai, Mar 3 2016, In : Expert Opinion on Therapeutic Patents. 26, 3, p. 323-345 23 p.

    Research output: Contribution to journalReview article

  11. 2015
  12. Published

    Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants

    Rami A. Al-Horani, David Gailani & Umesh R. Desai, Aug 1 2015, In : Thrombosis research. 136, 2, p. 379-387 9 p.

    Research output: Contribution to journalArticle

  13. 2014
  14. Published

    Recent Advances on Plasmin Inhibitors for the Treatment of Fibrinolysis-Related Disorders

    Rami A. Al-Horani & Umesh R. Desai, Nov 1 2014, In : Medicinal Research Reviews. 34, 6, p. 1168-1216 49 p.

    Research output: Contribution to journalArticle

  15. Published

    Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides

    Rami A. Al-Horani & Umesh R. Desai, Jun 12 2014, In : Journal of Medicinal Chemistry. 57, 11, p. 4805-4818 14 p.

    Research output: Contribution to journalArticle

  16. 2013
  17. Published

    Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site

    Rajesh Karuturi, Rami A. Al-Horani, Shrenik C. Mehta, David Gailani & Umesh R. Desai, Mar 28 2013, In : Journal of Medicinal Chemistry. 56, 6, p. 2415-2428 14 p.

    Research output: Contribution to journalArticle

  18. Published

    Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa

    Rami A. Al-Horani, Pooja Ponnusamy, Akul Y. Mehta, David Gailani & Umesh R. Desai, Feb 14 2013, In : Journal of Medicinal Chemistry. 56, 3, p. 867-878 12 p.

    Research output: Contribution to journalArticle