Christine Kern

Person

  1. 2019
  2. Published

    Adamts5 -/- mice exhibit altered aggrecan proteolytic profiles that correlate with ascending aortic anomalies

    Loren E. Dupuis, E. Lockett Nelson, Brittany Hozik, Sarah C. Porto, Alexandra Rogers-Decotes, Amanda Fosang & 1 others, Christine B. Kern, Oct 1 2019, In : Arteriosclerosis, thrombosis, and vascular biology. 39, 10, p. 2067-2081 15 p.

    Research output: Contribution to journalArticle

  3. 2018
  4. Published

    The Zonal Architecture of the Mandibular Condyle Requires ADAMTS5

    A. W. Rogers, S. E. Cisewski & C. B. Kern, Nov 1 2018, In : Journal of Dental Research. 97, 12, p. 1383-1390 8 p.

    Research output: Contribution to journalArticle

  5. 2017
  6. Published

    Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease

    P. M. Angel, D. A. Narmoneva, M. K. Sewell-Loftin, C. Munjal, L. Dupuis, B. J. Landis & 6 others, A. Jegga, C. B. Kern, W. D. Merryman, H. S. Baldwin, G. M. Bressan & Robert B. Hinton, Nov 1 2017, In : Annals of biomedical engineering. 45, 11, p. 2548-2562 15 p.

    Research output: Contribution to journalArticle

  7. 2015
  8. Published

    Lumican deficiency results in cardiomyocyte hypertrophy with altered collagen assembly

    Loren E. Dupuis, Matthew G. Berger, Samuel Feldman, Lorna Doucette, Vennece Fowlkes, Shukti Chakravarti & 4 others, Sarah Thibaudeau, Nicolas E. Alcala, Amy Dodd Bradshaw & Christine B Kern, Jul 1 2015, In : Journal of Molecular and Cellular Cardiology. 84, p. 70-80 11 p.

    Research output: Contribution to journalArticle

  9. Published

    Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction

    Santhosh K. Mani, Christine B. Kern, Denise Kimbrough, Benjamin Addy, Harinath Kasiganesan, William T. Rivers & 5 others, Risha K. Patel, James C. Chou, Francis G. Spinale, Rupak Mukherjee & Donald R. Menick, Jun 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 308, 11, p. H1391-H1401

    Research output: Contribution to journalArticle

  10. 2014
  11. Published

    Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development

    Loren E. Dupuis & Christine B. Kern, Apr 2014, In : Developmental Dynamics. 243, 4, p. 601-611 11 p.

    Research output: Contribution to journalArticle

  12. Published

    Imbalanced expression of vcan mrna splice form proteins alters heart morphology and cellular protein profiles

    Tara A. Burns, Maria T. Dours-Zimmermann, Dieter R. Zimmermann, Edward L. Krug, Susana Comte-Walters, Leticia Reyes & 5 others, Monica A. Davis, Kevin L. Schey, John H. Schwacke, Christine B. Kern & Corey H. Mjaatvedt, Feb 20 2014, In : PloS one. 9, 2, e89133.

    Research output: Contribution to journalArticle

  13. 2013
  14. Published

    Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves

    Loren E. Dupuis, Hanna Osinska, Michael B. Weinstein, Robert B Hinton & Christine B Kern, Jul 1 2013, In : Journal of Molecular and Cellular Cardiology. 60, 1, p. 50-59 10 p.

    Research output: Contribution to journalArticle

  15. 2012
  16. Published

    Maladaptive matrix remodeling and regional biomechanical dysfunction in a mouse model of aortic valve disease

    Varun Kumar Krishnamurthy, Amy M. Opoka, Christine B Kern, Farshid Guilak, Daria A. Narmoneva & Robert B Hinton, Apr 1 2012, In : Matrix Biology. 31, 3, p. 197-205 9 p.

    Research output: Contribution to journalArticle

  17. Published

    Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation

    Marion A. Cooley, Victor M. Fresco, Margaret E. Dorlon, Waleed O. Twal, Nathan V. Lee, Jeremy L. Barth & 3 others, Christine B. Kern, M. Luisa Iruela-Arispe & W. Scott Argraves, Feb 1 2012, In : Developmental Dynamics. 241, 2, p. 303-314 12 p.

    Research output: Contribution to journalArticle

  18. 2011
  19. Published

    Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease

    Loren E. Dupuis, Daniel R. McCulloch, Jessica D. McGarity, Alexandria Bahan, Andy Wessels, Deidra Weber & 4 others, A. Megan Diminich, Courtney M. Nelson, Suneel S. Apte & Christine B. Kern, Sep 1 2011, In : Developmental Biology. 357, 1, p. 152-164 13 p.

    Research output: Contribution to journalArticle