Evan Dale Abel

Person

  1. 2019
  2. Published

    Airway epithelial regeneration requires autophagy and glucose metabolism

    Kuan Li, Minmin Li, Wenli Li, Hongzhi Yu, Xin Sun, Qiuyang Zhang & 6 others, Yu Li, Xue Li, Yue Li, E. Dale Abel, Qi Wu & Huaiyong Chen, Dec 1 2019, In : Cell Death and Disease. 10, 12, 875.

    Research output: Contribution to journalArticle

  3. Published

    Increased glycolysis mediates Wnt7b-induced bone formation

    Hong Chen, Xing Ji, Wen Chih Lee, Yu Shi, Boer Li, E. Dale Abel & 3 others, Dianming Jiang, Wei Huang & Fanxin Long, Jul 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 7, p. 7810-7821 12 p.

    Research output: Contribution to journalArticle

  4. Published

    Comparison of the Effects of High-Fat Diet on Energy Flux in Mice Using Two Multiplexed Metabolic Phenotyping Systems

    Jamie E. Soto, Colin M.L. Burnett, Patrick Ten Eyck, E. Dale Abel & Justin L. Grobe, May 2019, In : Obesity. 27, 5, p. 793-802 10 p.

    Research output: Contribution to journalArticle

  5. Published

    Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure

    Joel L. Berry, Wuqiang Zhu, Yao Liang Tang, Prasanna Krishnamurthy, Ying Ge, John P. Cooke & 27 others, Yabing Chen, Daniel J. Garry, Huang Tian Yang, Namakkal Soorapan Rajasekaran, Walter J. Koch, Song Li, Keitaro Domae, Gangjian Qin, Ke Cheng, Timothy J. Kamp, Lei Ye, Shijun Hu, Brenda M. Ogle, Jack M. Rogers, E. Dale Abel, Michael E. Davis, Sumanth D. Prabhu, Ronglih Liao, William T. Pu, Yibin Wang, Peipei Ping, Nenad Bursac, Gordana Vunjak-Novakovic, Joseph C. Wu, Roberto Bolli, Philippe Menasché & Jianyi Zhang, Jan 4 2019, In : Circulation research. 124, 1, p. 161-169 9 p.

    Research output: Contribution to journalReview article

  6. Published

    Heart Failure in Type 2 Diabetes Mellitus: Impact of Glucose-Lowering Agents, Heart Failure Therapies, and Novel Therapeutic Strategies

    Helena C. Kenny & E. Dale Abel, Jan 4 2019, In : Circulation research. 124, 1, p. 121-141 21 p.

    Research output: Contribution to journalReview article

  7. Published

    Myeloid SLC2a1-deficient murine model revealed macrophage activation and metabolic phenotype are fueled by GLUT1

    Alex J. Freemerman, Liyang Zhao, Ajeeth K. Pingili, Bin Teng, Alyssa J. Cozzo, Ashley M. Fuller & 17 others, Amy R. Johnson, J. Justin Milner, Maili F. Lim, Joseph A. Galanko, Melinda A. Beck, James E. Bear, Jeremy D. Rotty, Lavanya Bezavada, Heather S. Smallwood, Michelle A. Puchowicz, Juan Liu, Jason W. Locasale, Douglas P. Lee, Brian J. Bennett, E. Dale Abel, Jeff C. Rathmell & Liza Makowski, Jan 1 2019, In : Journal of Immunology. 202, 4, p. 1265-1286 22 p.

    Research output: Contribution to journalArticle

  8. 2018
  9. Published

    Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission

    Kensuke Tsushima, Heiko Bugger, Adam R. Wende, Jamie Soto, Gregory A. Jenson, Austin R. Tor & 17 others, Rose McGlauflin, Helena C. Kenny, Yuan Zhang, Rhonda Souvenir, Xiao X. Hu, Crystal L. Sloan, Renata O. Pereira, Vitor A. Lira, Kenneth W. Spitzer, Terry L. Sharp, Kooresh I. Shoghi, Genevieve C. Sparagna, Eva A. Rog-Zielinska, Peter Kohl, Oleh Khalimonchuk, Jean E. Schaffer & E. Dale Abel, Jan 5 2018, In : Circulation research. 122, 1, p. 58-73 16 p.

    Research output: Contribution to journalArticle

  10. Published

    Effective metabolic approaches for the energy starved failing heart: Bioenergetic resiliency via redundancy or something else?

    Jianyi Zhang & E. Dale Abel, Jan 1 2018, In : Circulation research. 123, 3, p. 329-331 3 p.

    Research output: Contribution to journalArticle

  11. 2017
  12. Published

    Activation of IGF-1 receptors and Akt signaling by systemic hyperinsulinemia contributes to cardiac hypertrophy but does not regulate cardiac autophagy in obese diabetic mice

    Karla Maria Pires, Marcio Buffolo, Christin Schaaf, J. David Symons, James Cox, E. Dale Abel & 2 others, Craig H. Selzman & Sihem Boudina, Dec 2017, In : Journal of Molecular and Cellular Cardiology. 113, p. 39-50 12 p.

    Research output: Contribution to journalArticle

  13. Published

    Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses

    Adam R. Wende, Jaetaek Kim, William L. Holland, Benjamin E. Wayment, Brian T. O’Neill, Joseph Tuinei & 7 others, Manoja K. Brahma, Mark E. Pepin, Mark A. McCrory, Ivan Luptak, Ganesh V. Halade, Sheldon E. Litwin & E. Dale Abel, Dec 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 313, 6, p. H1098-H1108

    Research output: Contribution to journalArticle

  14. Published

    Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4

    Benjamin Steinhorn, Juliano L. Sartoretto, Andrea Sorrentino, Natalia Romero, Hermann Kalwa, E. Dale Abel & 1 others, Thomas Michel, Dec 2017, In : Free Radical Biology and Medicine. 113, p. 16-25 10 p.

    Research output: Contribution to journalArticle

  15. Published

    Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation

    Trevor P. Fidler, Elizabeth A. Middleton, Jesse W. Rowley, Luc H. Boudreau, Robert A. Campbell, Rhonda Souvenir & 5 others, Trevor Funari, Nicolas Tessandier, Eric Boilard, Andrew S. Weyrich & E. Dale Abel, Sep 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 9, p. 1628-1639 12 p.

    Research output: Contribution to journalArticle

  16. Published

    Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart

    Graham R. McGinnis, Yawen Tang, Rachel A. Brewer, Manoja K. Brahma, Haley L. Stanley, Gobinath Shanmugam & 11 others, Namakkal Soorappan Rajasekaran, Glenn C. Rowe, Stuart J. Frank, Adam R. Wende, E. Dale Abel, Heinrich Taegtmeyer, Silvio Litovsky, Victor Darley-Usmar, Jianhua Zhang, John C. Chatham & Martin E. Young, Sep 2017, In : Journal of Molecular and Cellular Cardiology. 110, p. 80-95 16 p.

    Research output: Contribution to journalArticle

  17. Published

    Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function

    Trevor P. Fidler, Robert A. Campbell, Trevor Funari, Nicholas Dunne, Enrique Balderas Angeles, Elizabeth A. Middleton & 3 others, Dipayan Chaudhuri, Andrew S. Weyrch & E. Dale Abel, Jul 25 2017, In : Cell reports. 20, 4, p. 881-894 14 p.

    Research output: Contribution to journalArticle

  18. Published

    OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance

    Renata Oliveira Pereira, Satya M. Tadinada, Frederick M. Zasadny, Karen Jesus Oliveira, Karla Maria Pereira Pires, Angela Olvera & 10 others, Jennifer Jeffers, Rhonda Souvenir, Rose McGlauflin, Alec Seei, Trevor Funari, Hiromi Sesaki, Matthew J. Potthoff, Christopher M. Adams, Ethan J. Anderson & E. Dale Abel, Jul 2017, In : EMBO Journal. 36, 14, p. 2126-2145 20 p.

    Research output: Contribution to journalArticle

  19. Published

    SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis

    Yanhui Zhang, Litao Xie, Susheel K. Gunasekar, Dan Tong, Anil Mishra, William J. Gibson & 9 others, Chuansong Wang, Trevor Fidler, Brodie Marthaler, Aloysius Klingelhutz, E. Dale Abel, Isaac Samuel, Jessica K. Smith, Lei Cao & Rajan Sah, May 1 2017, In : Nature cell biology. 19, 5, p. 504-517 14 p.

    Research output: Contribution to journalArticle

  20. Published

    Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling

    Amy K. Rines, Hsiang Chun Chang, Rongxue Wu, Tatsuya Sato, Arineh Khechaduri, Hidemichi Kouzu & 10 others, Jason Shapiro, Meng Shang, Michael A. Burke, Xinghang Jiang, Chunlei Chen, Tenley A. Rawlings, Gary D. Lopaschuk, Paul T. Schumacker, E. Dale Abel & Hossein Ardehali, Jan 24 2017, In : Nature communications. 8, 14095.

    Research output: Contribution to journalArticle

  21. Published

    Inhibiting insulin-mediated β 2-adrenergic receptor activation prevents diabetes-associated cardiac dysfunction

    Qingtong Wang, Yongming Liu, Qin Fu, Bing Xu, Yuan Zhang, Sungjin Kim & 7 others, Ruensern Tan, Federica Barbagallo, Toni West, Ethan Anderson, Wei Wei, E. Dale Abel & Yang K. Xiang, Jan 3 2017, In : Circulation. 135, 1, p. 73-88 16 p.

    Research output: Contribution to journalArticle

  22. 2016
  23. Published

    Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning

    Nikolaos A. Diakos, Sutip Navankasattusas, Evan Dale Abel, Jared Rutter, Lauren McCreath, Peter Ferrin & 12 others, Stephen H. McKellar, Dylan V. Miller, Song Y. Park, Russell S. Richardson, Ralph Deberardinis, James E. Cox, Abdallah G. Kfoury, Craig H Selzman, Josef Stehlik, James C. Fang, Dean Y. Li & Stavros G Drakos, Oct 1 2016, In : JACC: Basic to Translational Science. 1, 6, p. 432-444 13 p.

    Research output: Contribution to journalArticle

  24. 2015
  25. Published

    Phosphoinositide dependent protein kinase 1 is required for exercise-induced cardiac hypertrophy but not the associated mitochondrial adaptations

    Junghyun Noh, Adam R. Wende, Curtis D. Olsen, Bumjun Kim, Jack Bevins, Yi Zhu & 3 others, Quan Jiang Zhang, Christian Riehle & E. Dale Abel, Dec 1 2015, In : Journal of Molecular and Cellular Cardiology. 89, p. 297-305 9 p.

    Research output: Contribution to journalArticle

  26. Published

    Ceramide-initiated protein phosphatase 2A activation contributes to arterial dysfunction in vivo

    Leena P. Bharath, Ting Ruan, Youyou Li, Anindita Ravindran, Xin Wan, Jennifer Kim Nhan & 15 others, Matthew Lewis Walker, Lance Deeter, Rebekah Goodrich, Elizabeth Johnson, Derek Munday, Robert Mueller, David Kunz, Deborah Jones, Van Reese, Scott A. Summers, Pon Velayutham Anandh Babu, William L. Holland, Quan Jiang Zhang, E. Dale Abel & J. David Symons, Nov 2015, In : Diabetes. 64, 11, p. 3914-3926 13 p.

    Research output: Contribution to journalArticle

  27. Published

    Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis

    Xudong Liao, Rongli Zhang, Yuan Lu, Domenick A. Prosdocimo, Panjamaporn Sangwung, Lilei Zhang & 13 others, Guangjin Zhou, Puneet Anand, Ling Lai, Teresa C. Leone, Hisashi Fujioka, Fang Ye, Mariana G. Rosca, Charles L. Hoppel, P. Christian Schulze, E. Dale Abel, Jonathan S. Stamler, Daniel P. Kelly & Mukesh K. Jain, Sep 1 2015, In : Journal of Clinical Investigation. 125, 9, p. 3461-3476 16 p.

    Research output: Contribution to journalArticle

  28. Published

    Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity

    Bharat Jaishy, Quanjiang Zhang, Heaseung S. Chung, Christian Riehle, Jamie Soto, Stephen Jenkins & 4 others, Patrick Abel, L. Ashley Cowart, Jennifer E. Van Eyk & E. Dale Abel, Mar 1 2015, In : Journal of lipid research. 56, 3, p. 546-561 16 p.

    Research output: Contribution to journalArticle

  29. 2014
  30. Published

    Insulin inhibits cardiac contractility by inducing a Gi-Biased β2-adrenergic signaling in hearts

    Qin Fu, Bing Xu, Yongming Liu, Dippal Parikh, Jing Li, Ying Li & 9 others, Yuan Zhang, Christian Riehle, Yi Zhu, Tenley Rawlings, Qian Shi, Richard B. Clark, Xiongwen Chen, E. Dale Abel & Yang K. Xiang, Aug 2014, In : Diabetes. 63, 8, p. 2676-2689 14 p.

    Research output: Contribution to journalArticle

  31. Published

    Maintaining PGC-1α expression following pressure overload-induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function

    Renata O. Pereira, Adam R. Wende, Ashley Crum, Douglas Hunter, Curtis D. Olsen, Tenley Rawlings & 3 others, Christian Riehle, Walter F. Ward & E. Dale Abel, Aug 2014, In : FASEB Journal. 28, 8, p. 3691-3702 12 p.

    Research output: Contribution to journalArticle

  32. Published

    GLUT1 deficiency in cardiomyocytes does not accelerate the transition from compensated hypertrophy to heart failure

    Renata O. Pereira, Adam R. Wende, Curtis Olsen, Jamie Soto, Tenley Rawlings, Yi Zhu & 2 others, Christian Riehle & E. Dale Abel, Jul 2014, In : Journal of Molecular and Cellular Cardiology. 72, p. 95-103 9 p.

    Research output: Contribution to journalArticle

  33. Published

    Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the AktmTOR-NFkB-Opa-1 signaling pathway

    Valentina Parra, Hugo E. Verdejo, Myriam Iglewski, Andrea Del Campo, Rodrigo Troncoso, Deborah Jones & 15 others, Yi Zhu, Jovan Kuzmicic, Christian Pennanen, Camila Lopez-Crisosto, Fabián Jaña, Jorge Ferreira, Eduard Noguera, Mario Chiong, David A. Bernlohr, Amira Klip, Joseph A. Hill, Beverly A. Rothermel, Evan Dale Abel, Antonio Zorzano & Sergio Lavandero, Jan 1 2014, In : Diabetes. 63, 1, p. 75-88 14 p.

    Research output: Contribution to journalArticle

  34. Published

    Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training

    Christian Riehle, Adam R. Wende, Yi Zhu, Karen J. Oliveira, Renata O. Pereira, Bharat P. Jaishy & 11 others, Jack Bevins, Steven Valdez, Junghyun Noh, Bum Jun Kim, Annie Bello Moreira, Eric T. Weatherford, Rajkumar Manivel, Tenley A. Rawlings, Monika Rech, Morris F. White & E. Dale Abel, 2014, In : Molecular and cellular biology. 34, 18, p. 3450-3460 11 p.

    Research output: Contribution to journalArticle

  35. 2013
  36. Published

    Insulin receptor substrate signaling suppresses neonatal autophagy in the heart

    Christian Riehle, Adam R. Wende, Sandra Sena, Karla M. Pires, Renata O. Pereira, Yi Zhu & 13 others, Heiko Bugger, Deborah Frank, Jack Bevins, Dong Chen, Cynthia N. Perry, Xiaocheng C. Dong, Steven Valdez, Monika Rech, Xiaoming Sheng, Bart C. Weimer, Roberta A. Gottlieb, Morris F. White & E. D. Abel, Dec 2 2013, In : Journal of Clinical Investigation. 123, 12, p. 5319-5333 15 p.

    Research output: Contribution to journalArticle

  37. Published

    Insulin suppresses ischemic preconditioning-mediated cardioprotection through Akt-dependent mechanisms

    Tanner M. Fullmer, Shaobo Pei, Yi Zhu, Crystal Sloan, Robert Manzanares, Brandon Henrie & 4 others, Karla M. Pires, James E. Cox, E. Dale Abel & Sihem Boudina, Nov 1 2013, In : Journal of Molecular and Cellular Cardiology. 64, p. 20-29 10 p.

    Research output: Contribution to journalArticle

  38. Published

    Nrf2 deficiency prevents reductive stress-induced hypertrophic cardiomyopathy

    Sankaranarayanan Kannan, Vasanthi R. Muthusamy, Kevin J. Whitehead, Li Wang, Aldrin V. Gomes, Sheldon E. Litwin & 4 others, Thomas W. Kensler, E. Dale Abel, John R. Hoidal & Namakkal S. Rajasekaran, Oct 1 2013, In : Cardiovascular research. 100, 1, p. 63-73 11 p.

    Research output: Contribution to journalArticle

  39. Published

    Talini has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload

    Ana Maria Manso, Ruixia Li, Susan J. Monkley, Nathalia M. Cruz, Shannon Ong, Dieu H. Lao & 8 others, Yevgeniya E. Koshman, Yusu Gu, Kirk L. Peterson, Ju Chen, E. Dale Abel, Allen M. Samarel, David R. Critchley & Robert S. Ross, Feb 8 2013, In : Journal of Biological Chemistry. 288, 6, p. 4252-4264 13 p.

    Research output: Contribution to journalArticle

  40. Published

    Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation

    Yi Zhu, Renata O. Pereira, Brian T. O'Neill, Christian Riehle, Olesya Ilkun, Adam R. Wende & 7 others, Tenley A. Rawlings, Yi Cheng Zhang, Quanjiang Zhang, Amira Klip, Ichiro Shiojima, Kenneth Walsh & E. Dale Abel, Jan 7 2013, In : Molecular Endocrinology. 27, 1, p. 172-184 13 p.

    Research output: Contribution to journalArticle

  41. Published

    Inducible overexpression of GLUT1 prevents mitochondrial dysfunction and attenuates structural remodeling in pressure overload but does not prevent left ventricular dysfunction

    Renata O. Pereira, Adam R. Wende, Curtis Olsen, Jamie Soto, Tenley Rawlings, Yi Zhu & 2 others, Steven M. Anderson & E. Dale Abel, Jan 1 2013, In : Journal of the American Heart Association. 2, 5, e000301.

    Research output: Contribution to journalArticle

  42. 2012
  43. Published

    Impaired Transcriptional Activity of Nrf2 in Age-Related Myocardial Oxidative Stress Is Reversible by Moderate Exercise Training

    Sellamuthu S. Gounder, Sankaranarayanan Kannan, Dinesh Devadoss, Corey J. Miller, Kevin S. Whitehead, Shannon J. Odelberg & 5 others, Matthew A. Firpo, Robert Paine, John R. Hoidal, E. Dale Abel & Namakkal S. Rajasekaran, Sep 24 2012, In : PloS one. 7, 9, e45697.

    Research output: Contribution to journalArticle

  44. Published

    Ceramide mediates vascular dysfunction in diet-induced obesity by PP2A-mediated dephosphorylation of the eNOS-Akt complex

    Quan Jiang Zhang, William L. Holland, Lloyd Wilson, Jason M. Tanner, Devin Kearns, Judd M. Cahoon & 18 others, Dix Pettey, Jason Losee, Bradlee Duncan, Derrick Gale, Christopher A. Kowalski, Nicholas Deeter, Alexandrea Nichols, Michole Deesing, Colton Arrant, Ting Ruan, Christoph Boehme, Dane R. McCamey, Janvida Rou, Kapil Ambal, Krishna K. Narra, Scott A. Summers, E. Dale Abel & J. David Symons, Jul 1 2012, In : Diabetes. 61, 7, p. 1848-1859 12 p.

    Research output: Contribution to journalArticle

  45. Published

    Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5.

    Jenny X. Chen, Markus Krane, Marcus Andre Deutsch, L. Wang, Moshe Rav-Acha, Serge Gregoire & 7 others, Marc C. Engels, Kuppusamy Rajarajan, Ravi Karra, E. Dale Abel, Joe C. Wu, David Milan & Sean M. Wu, Jun 22 2012, In : Circulation research. 111, 1, p. 50-55 6 p.

    Research output: Contribution to journalArticle

  46. Published

    Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity

    Sihem Boudina, Sandra Sena, Crystal Sloan, Ali Tebbi, Yong Hwan Han, Brian T. O'Neill & 5 others, Robert C. Cooksey, Deborah Jones, William L. Holland, Donald A. McClain & E. Dale Abel, Jun 1 2012, In : Endocrinology. 153, 6, p. 2677-2688 12 p.

    Research output: Contribution to journalArticle

  47. 2011
  48. Published

    Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo

    Christian D. Young, Andrew S. Lewis, Michael C. Rudolph, Marisa D. Ruehle, Matthew R. Jackman, Ui J. Yun & 4 others, Olesya Ilkun, Renata Pereira, E. Dale Abel & Steven M. Anderson, Aug 8 2011, In : PloS one. 6, 8, e23205.

    Research output: Contribution to journalArticle