Isabelle Deschenes

Person

  1. 2019
  2. Published

    Dynamic palmitoylation regulates trafficking of K channel interacting protein 2 (KChIP2) across multiple subcellular compartments in cardiac myocytes

    Akshay Murthy, Samuel W. Workman, Min Jiang, Junping Hu, I. Sifa, T. Bernas & 3 others, Wanchun Tang, Isabelle Deschenes & Gea Ny Tseng, Oct 2019, In : Journal of Molecular and Cellular Cardiology. 135, p. 1-9 9 p.

    Research output: Contribution to journalArticle

  3. 2018
  4. Published

    S-phase synchronization facilitates the early progression of induced-cardiomyocyte reprogramming through enhanced cell-cycle exit

    Emre Bektik, Adrienne Dennis, Gary Pawlowski, Chen Zhou, Danielle Maleski, Satoru Takahashi & 3 others, Kenneth R. Laurita, Isabelle Deschênes & Ji Dong Fu, May 4 2018, In : International journal of molecular sciences. 19, 5, 1364.

    Research output: Contribution to journalArticle

  5. Published

    Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity

    Sam Chai, Xiaoping Wan, Angelina Ramirez-Navarro, Paul J. Tesar, Elizabeth S. Kaufman, Eckhard Ficker & 2 others, Alfred L. George & Isabelle Deschênes, Mar 1 2018, In : Journal of Clinical Investigation. 128, 3, p. 1043-1056 14 p.

    Research output: Contribution to journalArticle

  6. 2017
  7. Published

    Voltage-gated sodium channels assemble and gate as dimers

    Jérôme Clatot, Malcolm Hoshi, Xiaoping Wan, Haiyan Liu, Ankur Jain, Krekwit Shinlapawittayatorn & 4 others, Céline Marionneau, Eckhard Ficker, Taekjip Ha & Isabelle Deschênes, Dec 1 2017, In : Nature communications. 8, 1, 2077.

    Research output: Contribution to journalArticle

  8. Published

    A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1 –Induced Activation of Pacemaker Current

    Yu Sun, Valeriy Timofeyev, Adrienne Dennis, Emre Bektik, Xiaoping Wan, Kenneth R. Laurita & 3 others, Isabelle Deschênes, Ronald A. Li & Ji Dong Fu, Oct 1 2017, In : Stem Cell Reviews and Reports. 13, 5, p. 631-643 13 p.

    Research output: Contribution to journalArticle

  9. Published

    Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics

    Nipavan Chiamvimonvat, Ye Chen-Izu, Colleen E. Clancy, Isabelle Deschenes, Dobromir Dobrev, Jordi Heijman & 11 others, Leighton Izu, Zhilin Qu, Crystal M. Ripplinger, Jamie I. Vandenberg, James N. Weiss, Gideon Koren, Tamas Banyasz, Eleonora Grandi, Michael C. Sanguinetti, Donald M. Bers & Jeanne M. Nerbonne, Apr 1 2017, In : Journal of Physiology. 595, 7, p. 2229-2252 24 p.

    Research output: Contribution to journalArticle

  10. Published

    KChIP2 regulates the cardiac Ca2+ transient and myocyte contractility by targeting ryanodine receptor activity

    Drew M. Nassal, Xiaoping Wan, Haiyan Liu, Kenneth R. Laurita & Isabelle Deschênes, Apr 2017, In : PloS one. 12, 4, e0175221.

    Research output: Contribution to journalArticle

  11. Published

    KChIP2 is a core transcriptional regulator of cardiac excitability

    Drew M. Nassal, Xiaoping Wan, Haiyan Liu, Danielle Maleski, Angelina Ramirez-Navarro, Christine S. Moravec & 3 others, Eckhard Ficker, Kenneth R. Laurita & Isabelle Deschênes, Mar 6 2017, In : eLife. 6, e17304.

    Research output: Contribution to journalArticle

  12. Published

    KChIP2 is a core transcriptional regulator of cardiac excitability

    Drew M. Nassal, Xiaoping Wan, Haiyan Liu, Danielle Maleski, Angelina Ramirez-Navarro, Christine S. Moravec & 3 others, Eckhard Ficker, Kenneth R. Laurita & Isabelle Deschênes, Mar 6 2017, In : eLife. 6

    Research output: Contribution to journalArticle

  13. Published

    Contribution of two-pore K+ channels to cardiac ventricular action potential revealed using human iPSC-derived cardiomyocytes

    Sam Chai, Xiaoping Wan, Drew M. Nassal, Haiyan Liu, Christine S. Moravec, Angelina Ramirez-Navarro & 1 others, Isabelle Deschênes, Jan 1 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 312, 6, p. H1144-H1153

    Research output: Contribution to journalArticle

  14. 2016
  15. Published

    Myocardial KChIP2 expression in Guinea pig resolves an expanded electrophysiologic role

    Drew M. Nassal, Xiaoping Wan, Haiyan Liu & Isabelle Deschênes, Jan 1 2016, In : PloS one. 11, 1, e0146561.

    Research output: Contribution to journalArticle

  16. 2014
  17. Published

    A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation

    Azza Ziyadeh-Isleem, Jérôme Clatot, Sabine Duchatelet, Estelle Gandjbakhch, Isabelle Denjoy, Françoise Hidden-Lucet & 5 others, Stéphane Hatem, Isabelle Deschênes, Alain Coulombe, Nathalie Neyroud & Pascale Guicheney, Jun 2014, In : Heart Rhythm. 11, 6, p. 1015-1023 9 p.

    Research output: Contribution to journalArticle

  18. Published

    Brugada syndrome disease phenotype explained in apparently benign sodium channel mutations

    Malcolm Hoshi, Xi X. Du, Krekwit Shinlapawittayatorn, Haiyan Liu, Sam Chai, Xiaoping Wan & 2 others, Eckhard Ficker & Isabelle Deschênes, Apr 2014, In : Circulation: Cardiovascular Genetics. 7, 2, p. 123-131 9 p.

    Research output: Contribution to journalArticle

  19. Published

    Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis

    Shenaz Khan, Bassam G Abu Jawdeh, Monu Goel, William P. Schilling, Mark D. Parker, Michelle A. Puchowicz & 8 others, Satya P. Yadav, Raymond C. Harris, Ashraf El-Meanawy, Malcolm Hoshi, Krekwit Shinlapawittayatorn, Isabelle Deschenes, Eckhard Ficker & Jeffrey R. Schelling, Mar 3 2014, In : Journal of Clinical Investigation. 124, 3, p. 1057-1068 12 p.

    Research output: Contribution to journalArticle

  20. 2013
  21. Published

    Ionic bases for electrical remodeling of the canine cardiac ventricle

    Darwin Jeyaraj, Xiaoping Wan, Eckhard Ficker, Julian E. Stelzer, Isabelle Deschenes, Haiyan Liu & 6 others, Lance D. Wilson, Keith F. Decker, Tamer H. Said, Mukesh K. Jain, Yoram Rudy & David S. Rosenbaum, Aug 1 2013, In : American Journal of Physiology - Heart and Circulatory Physiology. 305, 3, p. H410-H419

    Research output: Contribution to journalArticle

  22. Published

    Erratum: Wild-type sodium channels and 'Atypical' Brugada syndrome mutants interact through C-terminal region (Biophysical Journal (2013) 104:2 (133a))

    Malcolm Hoshi, Krekwit Shinlapawittayatorn, Sam Chai, Xi X. Du, Haiyan Liu, Xiaoping Wan & 2 others, Eckhard Ficker & Isabelle Deschenes, Apr 16 2013, In : Biophysical journal. 104, 8, 1 p.

    Research output: Contribution to journalComment/debate

  23. 2012
  24. Published

    Dominant-negative effect of SCN5A N-terminal mutations through the interaction of Nav1.5 α-subunits

    Jérôme Clatot, Azza Ziyadeh-Isleem, Svetlana Maugenre, Isabelle Denjoy, Haiyan Liu, Gilles Dilanian & 5 others, Stéphane N. Hatem, Isabelle Deschenes, Alain Coulombe, Pascale Guicheney & Nathalie Neyroud, Oct 1 2012, In : Cardiovascular research. 96, 1, p. 53-63 11 p.

    Research output: Contribution to journalArticle

  25. 2011
  26. Published

    A novel strategy using cardiac sodium channel polymorphic fragments to rescue trafficking-deficient SCN5A Mutations

    Krekwit Shinlapawittayatorn, Lynn A. Dudash, Xi X. Du, Lisa Heller, Steven Poelzing, Eckhard Ficker & 1 others, Isabelle Deschênes, Oct 1 2011, In : Circulation: Cardiovascular Genetics. 4, 5, p. 500-509 10 p.

    Research output: Contribution to journalArticle

  27. Published

    A common SCN5A polymorphism modulates the biophysical defects of SCN5A mutations

    Krekwit Shinlapawittayatorn, Xi X. Du, Haiyan Liu, Eckhard Ficker, Elizabeth S. Kaufman & Isabelle Deschênes, Mar 1 2011, In : Heart Rhythm. 8, 3, p. 455-462 8 p.

    Research output: Contribution to journalArticle