Leslie A Leinwand

Person

  1. 2019
  2. Published

    Differences in microRNA-29 and Pro-fibrotic Gene Expression in Mouse and Human Hypertrophic Cardiomyopathy

    Yamin Liu, Junaid Afzal, Styliani Vakrou, Gabriela V. Greenland, C. Conover Talbot, Virginia B. Hebl & 8 others, Yufan Guan, Rehan Karmali, Jil C. Tardiff, Leslie A. Leinwand, Jeffrey E. Olgin, Samarjit Das, Ryuya Fukunaga & M. Roselle Abraham, Dec 17 2019, In : Frontiers in Cardiovascular Medicine. 6, 170.

    Research output: Contribution to journalArticle

  3. Published

    Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties

    Carlos D. Vera, Chloe A. Johnson, Jonathan Walklate, Arjun Adhikari, Marina Svicevic, Srboljub M. Mijailovich & 6 others, Ariana C. Combs, Stephen J. Langer, Kathleen M. Ruppel, James A. Spudich, Michael A. Geeves & Leslie A. Leinwand, Nov 15 2019, In : Journal of Biological Chemistry. 294, 46, p. 17451-17462 12 p.

    Research output: Contribution to journalArticle

  4. Published

    The ATPase cycle of human muscle myosin II isoforms: Adaptation of a single mechanochemical cycle for different physiological roles

    Chloe A. Johnson, Jonathan Walklate, Marina Svicevic, Srboljub M. Mijailovich, Carlos Vera, Anastasia Karabina & 2 others, Leslie A. Leinwand & Michael A. Geeves, Sep 27 2019, In : Journal of Biological Chemistry. 294, 39, p. 14267-14278 12 p.

    Research output: Contribution to journalArticle

  5. Published

    Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation

    Brian A. Aguado, Katherine B. Schuetze, Joseph C. Grim, Cierra J. Walker, Anne C. Cox, Tova L. Ceccato & 5 others, Aik Choon Tan, Carmen C. Sucharov, Leslie A. Leinwand, Timothy A. McKinsey & Kristi S. Anseth, Sep 11 2019, In : Science Translational Medicine. 11, 509, eaav3233.

    Research output: Contribution to journalArticle

  6. Published

    The ancient sarcomeric myosins found in specialized muscles

    Lindsey A. Lee, Anastasia Karabina, Lindsey J. Broadwell & Leslie A. Leinwand, Mar 5 2019, In : Skeletal Muscle. 9, 1, 7.

    Research output: Contribution to journalReview article

  7. 2017
  8. Published

    Molecular Mechanisms Underlying Cardiac Adaptation to Exercise

    Rick B. Vega, John P. Konhilas, Daniel P. Kelly & Leslie A. Leinwand, May 2 2017, In : Cell metabolism. 25, 5, p. 1012-1026 15 p.

    Research output: Contribution to journalReview article

  9. Published

    Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro

    Susan M. Soto, Amy C. Blake, Stephanie R. Wesolowski, Paul J. Rozance, Kristen B. Barthel, Bifeng Gao & 7 others, Byron Hetrick, Carrie E. McCurdy, Natalia G. Garza, William W. Hay, Leslie A. Leinwand, Jacob E. Friedman & Laura D. Brown, Jan 1 2017, In : Journal of Endocrinology. 232, 3, p. 475-491 17 p.

    Research output: Contribution to journalArticle

  10. 2016
  11. Published

    Estrogen receptor profiling and activity in cardiac myocytes

    Emily K. Pugach, Christa L. Blenck, Joseph M. Dragavon, Stephen J. Langer & Leslie A. Leinwand, Aug 15 2016, In : Molecular and Cellular Endocrinology. 431, p. 62-70 9 p.

    Research output: Contribution to journalArticle

  12. Published

    The importance of biological sex and estrogen in rodent models of cardiovascular health and disease

    Christa L. Blenck, Pamela A. Harvey, Jane F. Reckelhoff & Leslie A. Leinwand, Apr 15 2016, In : Circulation research. 118, 8, p. 1294-1312 19 p.

    Research output: Contribution to journalReview article

  13. 2015
  14. Published

    Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic

    Emily K. Pugach, Phillip A. Richmond, Joseph G. Azofeifa, Robin D. Dowell & Leslie A. Leinwand, Sep 1 2015, In : Journal of Molecular and Cellular Cardiology. 86, p. 54-61 8 p.

    Research output: Contribution to journalArticle

  15. Published

    Oestrogen enhances cardiotoxicity induced by Sunitinib by regulation of drug transport and metabolism

    Pamela Ann Harvey & Leslie Anne Leinwand, Jul 1 2015, In : Cardiovascular research. 107, 1, p. 66-77 12 p.

    Research output: Contribution to journalArticle

  16. Published

    miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway

    Martin G. Guess, Kristen K.B. Barthel, Brooke C. Harrison & Leslie A. Leinwand, Feb 17 2015, In : PloS one. 10, 2, e0118229.

    Research output: Contribution to journalArticle

  17. Published

    Dietary phytoestrogens present in soy dramatically increase cardiotoxicity in male mice receiving a chemotherapeutic tyrosine kinase inhibitor

    Pamela Ann Harvey & Leslie Anne Leinwand, Jan 5 2015, In : Molecular and Cellular Endocrinology. 399, p. 330-335 6 p.

    Research output: Contribution to journalArticle

  18. 2014
  19. Published

    Pregnancy as a cardiac stress model

    Eunhee Chung & Leslie A. Leinwand, Jan 1 2014, In : Cardiovascular research. 101, 4, p. 561-570 10 p.

    Research output: Contribution to journalReview article

  20. 2013
  21. Published

    Calcineurin activity is required for cardiac remodelling in pregnancy

    Eunhee Chung, Fan Yeung & Leslie A. Leinwand, Dec 1 2013, In : Cardiovascular research. 100, 3, p. 402-410 9 p.

    Research output: Contribution to journalArticle

  22. 2012
  23. Published

    A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy

    Jorge L. Ruas, James P. White, Rajesh R. Rao, Sandra Kleiner, Kevin T. Brannan, Brooke C. Harrison & 11 others, Nicholas P. Greene, Jun Wu, Jennifer L. Estall, Brian A. Irving, Ian R. Lanza, Kyle A. Rasbach, Mitsuharu Okutsu, K. Sreekumaran Nair, Zhen Yan, Leslie A. Leinwand & Bruce M. Spiegelman, Dec 7 2012, In : Cell. 151, 6, p. 1319-1331 13 p.

    Research output: Contribution to journalArticle

  24. Published

    Interferon-γ causes cardiac myocyte atrophy via selective degradation of myosin heavy chain in a model of chronic myocarditis

    Pippa Cosper, Pamela Ann Harvey & Leslie A Leinwand, Dec 1 2012, In : American Journal of Pathology. 181, 6, p. 2038-2046 9 p.

    Research output: Contribution to journalArticle

  25. Published

    Estrogenic compounds are not always cardioprotective and can be lethal in males with genetic heart disease

    Christopher D. Haines, Pamela A. Harvey, Elizabeth D. Luczak, Kristen K.B. Barthel, John P. Konhilas, Peter A. Watson & 2 others, Brian L. Stauffer & Leslie A. Leinwand, Sep 1 2012, In : Endocrinology. 153, 9, p. 4470-4479 10 p.

    Research output: Contribution to journalArticle

  26. Published

    Distinct cardiac transcriptional profiles defining pregnancy and exercise

    Eunhee Chung, Joseph Heimiller & Leslie A. Leinwand, Jul 31 2012, In : PloS one. 7, 7, e42297.

    Research output: Contribution to journalArticle

  27. Published

    Myosin heavy chain is not selectively decreased in murine cancer cachexia

    Pippa F. Cosper & Leslie A. Leinwand, Jun 1 2012, In : International Journal of Cancer. 130, 11, p. 2722-2727 6 p.

    Research output: Contribution to journalArticle

  28. Published

    Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation

    Eunhee Chung, Fan Yeung & Leslie A. Leinwand, May 1 2012, In : Journal of applied physiology. 112, 9, p. 1564-1575 12 p.

    Research output: Contribution to journalArticle

  29. 2011
  30. Published

    Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension

    Douglas D. Lemon, Todd R. Horn, Maria A. Cavasin, Mark Y. Jeong, Kurt W. Haubold, Carlin S. Long & 5 others, David C. Irwin, Sylvia A. McCune, Eunhee Chung, Leslie A. Leinwand & Timothy A. McKinsey, Jul 1 2011, In : Journal of Molecular and Cellular Cardiology. 51, 1, p. 41-50 10 p.

    Research output: Contribution to journalArticle

  31. Published

    Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner

    Pippa Cosper & Leslie A Leinwand, Mar 1 2011, In : Cancer Research. 71, 5, p. 1710-1720 11 p.

    Research output: Contribution to journalArticle