Muhammad A Abdul-Ghani

Person

  1. 2019
  2. Published

    The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner

    Subramanya Srikantan, Yilun Deng, Zi Ming Cheng, Anqi Luo, Yuejuan Qin, Qing Gao & 16 others, Glaiza Mae Sande-Docor, Sifan Tao, Xingyu Zhang, Nathan Harper, Chris E. Shannon, Marcel Fourcaudot, Zhi Li, Balakuntalam S. Kasinath, Stephen Harrison, Sunil Ahuja, Robert L. Reddick, Lily Q. Dong, Muhammad Abdul-Ghani, Luke Norton, Ricardo C.T. Aguiar & Patricia L.M. Dahia, Dec 1 2019, In : Nature communications. 10, 1, 4720.

    Research output: Contribution to journalArticle

  3. Published

    Mild Physiologic Hyperglycemia Induces Hepatic Insulin Resistance in Healthy Normal Glucose-Tolerant Participants

    Devjit Tripathy, Aurora Merovci, Rita Basu, Muhammad Abdul-Ghani & Ralph A. Defronzo, Mar 21 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2842-2850 9 p., jcem_201802304.

    Research output: Contribution to journalArticle

  4. 2017
  5. Published

    Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects

    Roy Eldor, Luke Norton, Marcel Fourcaudot, Cynthia Galindo, Ralph A. DeFronzo & Muhammad Abdul-Ghani, Dec 2017, In : PloS one. 12, 12, e0188208.

    Research output: Contribution to journalArticle

  6. Published

    Hepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance

    Hongzhi Chen, Juli Bai, Feng Dong, Hezhi Fang, Yun Zhang, Wen Meng & 11 others, Bilian Liu, Yan Luo, Meilian Liu, Yidong Bai, Muhammad A. Abdul-Ghani, Rongxia Li, Jiarui Wu, Rong Zeng, Zhiguang Zhou, Lily Q. Dong & Feng Liu, Jun 2017, In : FASEB Journal. 31, 6, p. 2314-2326 13 p.

    Research output: Contribution to journalArticle

  7. Published

    Impact of ethnicity and obesity on insulin resistance in two ethnic groups at very high risk of type 2 diabetes

    S. Hassoun, M. Al-Atrash, M. Alkasim, Z. Dabbous, O. Mujahed, R. A. DeFronzo & 3 others, A. Jayyousi, M. Zirie & M. Abdul-Ghani, Jun 2017, In : Diabetes and Metabolism. 43, 3, p. 292-294 3 p.

    Research output: Contribution to journalLetter

  8. 2016
  9. Published

    Dapagliflozin enhances fat oxidation and ketone production in patients with type 2 diabetes

    Giuseppe Daniele, Juan Xiong, Carolina Solis-Herrera, Aurora Merovci, Roy Eldor, Devjit Tripathy & 3 others, Ralph A. DeFronzo, Luke Norton & Muhammad A Abdul-Ghani, Nov 1 2016, In : Diabetes care. 39, 11, p. 2036-2041 6 p.

    Research output: Contribution to journalArticle

  10. 2015
  11. Published

    Dapagliflozin lowers plasma glucose concentration and improves β-cell function

    Aurora Merovci, Andrea Mari, Carolina Solis, Ralph A. DeFronzo, Giuseppe Daniele, Alberto Chavez-Velazquez & 4 others, Devjit Tripathy, Scheherezada Urban McCarthy, Muhammad Abdul-Ghani & Juan Xiong, May 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1927-1932 6 p.

    Research output: Contribution to journalArticle

  12. Published

    Fiber orientation measurements by diffusion tensor imaging improve hydrogen-1 magnetic resonance spectroscopy of intramyocellular lipids in human leg muscles

    Sunil K. Valaparla, Feng Gao, Giuseppe Daniele, Muhammad Abdul-Ghani & Geoffrey D. Clarke, Apr 1 2015, In : Journal of Medical Imaging. 2, 2, 026002.

    Research output: Contribution to journalArticle

  13. Published

    Transcriptomic identification of adh1b as a novel candidate gene for obesity and insulin resistance in human adipose tissue in mexican americans from the veterans administration genetic epidemiology study (vages)

    Deidre A. Winnier, Marcel Fourcaudot, Luke Norton, Muhammad A. Abdul-Ghani, Shirley L. Hu, Vidya S. Farook & 16 others, Dawn K. Coletta, Satish Kumar, Sobha Puppala, Geetha Chittoor, Thomas D. Dyer, Rector Arya, Melanie Carless, Donna M. Lehman, Joanne E. Curran, Douglas T. Cromack, Devjit Tripathy, John Blangero, Ravindranath Duggirala, Harald H.H. Göring, Ralph A. DeFronzo & Christopher P. Jenkinson, Apr 1 2015, In : PloS one. 10, 4, 119941.

    Research output: Contribution to journalArticle

  14. 2014
  15. Published

    The disposition index does not reflect β-cell function in IGT subjects treated with pioglitazone

    Ralph A. Defronzo, Devjit Tripathy, Muhammad Abdul-Ghani, Nicolas Musi & Amalia Gastaldelli, Oct 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 10, p. 3774-3781 8 p.

    Research output: Contribution to journalArticle

  16. Published

    Chronic reduction of plasma free fatty acid improves mitochondrial function and whole-body insulin sensitivity in obese and type 2 diabetic individuals

    Giuseppe Daniele, Roy Eldor, Aurora Merovci, Geoffrey D. Clarke, Juan Xiong, Devjit Tripathy & 3 others, Anna Taranova, Muhammad Abdul-Ghani & Ralph A. DeFronzo, Aug 2014, In : Diabetes. 63, 8, p. 2812-2820 9 p.

    Research output: Contribution to journalArticle

  17. Published

    APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor

    Jiyoon Ryu, Amanda K. Galan, Xiaoban Xin, Feng Dong, Muhammad A. Abdul-Ghani, Lijun Zhou & 12 others, Changhua Wang, Cuiling Li, Bekke M. Holmes, Lauren B. Sloane, Steven N. Austad, Shaodong Guo, Nicolas Musi, Ralph A. DeFronzo, Chuxia Deng, Morris F. White, Feng Liu & Lily Q. Dong, May 22 2014, In : Cell reports. 7, 4, p. 1227-1238 12 p.

    Research output: Contribution to journalArticle

  18. Published

    Novel agents for the treatment of type 2 diabetes

    Ralph A. DeFronzo, Curtis L. Triplitt, Muhammad Abdul-Ghani & Eugenio Cersosimo, May 2014, In : Diabetes Spectrum. 27, 2, p. 100-112 13 p.

    Research output: Contribution to journalReview article

  19. Published

    Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production

    Aurora Merovci, Carolina Solis-Herrera, Giuseppe Daniele, Roy Eldor, Teresa Vanessa Fiorentino, Devjit Tripathy & 5 others, Juan Xiong, Zandra Perez, Luke Norton, Muhammad A. Abdul-Ghani & Ralph A. DeFronzo, Feb 3 2014, In : Journal of Clinical Investigation. 124, 2, p. 509-514 6 p.

    Research output: Contribution to journalArticle

  20. Published

    Intramyocellular lipid dependence on skeletal muscle fiber type and orientation characterized by diffusion tensor imaging and 1H-MRS

    Sunil K. Valaparla, Feng Gao, Muhammad Abdul-Ghani & Geoffrey D. Clarke, Jan 1 2014, Medical Imaging 2014: Image Processing. SPIE, 90340S. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9034).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  21. 2013
  22. Published

    Morbid obesity resulting from inactivation of the ciliary protein CEP19 in humans and mice

    Adel Shalata, Maria C. Ramirez, Robert J. Desnick, Nolan Priedigkeit, Christoph Buettner, Claudia Lindtner & 17 others, Mohammed Mahroum, Muhammad Abdul-Ghani, Feng Dong, Nazik Arar, Olga Camacho-Vanegas, Rui Zhang, Sandra C. Camacho, Ying Chen, Mwafaq Ibdah, Ralph Defronzo, Virginia Gillespie, Kevin Kelley, Brian D. Dynlacht, Sehyun Kim, Marc J. Glucksman, Zvi U. Borochowitz & John A. Martignetti, Dec 5 2013, In : American journal of human genetics. 93, 6, p. 1061-1071 11 p.

    Research output: Contribution to journalArticle

  23. Published

    Metabolic effects of bariatric surgery in patients with moderate obesity and type 2 diabetes: Analysis of a randomized control trial comparing surgery with intensive medical treatment

    Sangeeta R. Kashyap, Deepak L. Bhatt, Kathy Wolski, Richard M. Watanabe, Muhammad Abdul-Ghani, Beth Abood & 6 others, Claire E. Pothier, Stacy Brethauer, Steven Nissen, Manjula Gupta, John P. Kirwan & Philip R. Schauer, Oct 28 2013, In : Diabetes care. 36, 8, p. 2175-2182 8 p.

    Research output: Contribution to journalArticle

  24. Published

    Early metabolic defects in Arab subjects with strong family history of Type 2 diabetes

    A. Shalata, W. Jazmawi, O. Aslan, K. Badarni, K. Dabbah, S. Sawaed & 5 others, O. Cohen Castel, Z. U. Borochowitz, K. Karkabi, R. DeFronzo & M. Abdul-Ghani, Jun 1 2013, In : Journal of Endocrinological Investigation. 36, 6, p. 417-421 5 p.

    Research output: Contribution to journalArticle

  25. Published

    Type 2 diabetes and the evolving paradigm in glucose regulation

    Muhammad A Abdul-Ghani, Jan 1 2013, In : American Journal of Managed Care. 19, 3 SUPPL

    Research output: Contribution to journalArticle

  26. 2012
  27. Published

    Successful treatment of prediabetes in clinical practice: Targeting insulin resistance and β-cell dysfunction

    John Armato, Ralph A. Defronzo, Muhammad Abdul-Ghani & Ron Ruby, May 1 2012, In : Endocrine Practice. 18, 3, p. 342-350 9 p.

    Research output: Contribution to journalArticle

  28. 2011
  29. Published

    Impaired early- but not late-phase insulin secretion in subjects with impaired fasting glucose

    Mustafa Kanat, Luke Norton, Diedre Winnier, Chris Jenkinson, Ralph A. Defronzo & Muhammad A Abdul-Ghani, Sep 1 2011, In : Acta Diabetologica. 48, 3, p. 209-217 9 p.

    Research output: Contribution to journalArticle

  30. Published

    The relationship between β-cell function and glycated hemoglobin: Results from the veterans administration genetic epidemiology study

    Mustafa Kanat, Diedre Winnier, Luke Norton, Nazik Arar, Chris Jenkinson, Ralph A. Defronzo & 1 others, Muhammad A Abdul-Ghani, Apr 1 2011, In : Diabetes care. 34, 4, p. 1006-1010 5 p.

    Research output: Contribution to journalArticle