Depressive Symptom Trajectories Among People Living with HIV in a Collaborative Care Program

Research output: Contribution to journalArticle

Authors

  • Douglas Gunzler
  • Steven Lewis
  • Allison Webel
  • Mallika Lavakumar
  • Diana Gurley
  • Katherine Kulp
  • McKenzie K. Pile
  • Victoria El-Hayek
  • Ann Avery

External Institution(s)

  • Case Western Reserve University
  • Middlebury College
  • Wheaton College

Details

Original languageEnglish (US)
Pages (from-to)1765-1775
Number of pages11
JournalAIDS and Behavior
Volume24
Issue number6
StatusPublished - Jun 1 2020
Peer-reviewedYes

Abstract

Depressive symptoms may differ in severity and change over time in people living with HIV (PLWH). Describing depression trajectories and associated clinical characteristics of PLWH in an interventional study may help in developing a more personalized medicine approach. Using latent class growth analysis four, 15-month self-reported depression trajectories were identified in 416 PLWH participating in a collaborative care program. The four subgroups were characterized by improving (58.4% [of participants]), worsening (9.4%), highly responsive (19.5%) and persistently severe (12.7%) depressive symptoms. A high proportion of individuals were in trajectories marked by improvement. Further, the highly responsive group had on average, over 50% reduction of self-reported depressive symptoms. Self-reported trauma, posttraumatic stress disorder, lower neighborhood-level education and fewer HIV and psychiatry clinic visits were associated with worsening or persistently severe depressive symptom trajectories. Members of the persistently severe group were less likely to be virally suppressed after 12-months. Identifying subgroups of PLWH based on changes in self-reported depressive symptoms may further inform intervention approaches that can advance care.

    Research areas

  • Collaborative care model, Depression, HIV viral suppression, Latent class growth analysis, Longitudinal studies, Reported trauma

Citation formats

APA

Gunzler, D., Lewis, S., Webel, A., Lavakumar, M., Gurley, D., Kulp, K., ... Avery, A. (2020). Depressive Symptom Trajectories Among People Living with HIV in a Collaborative Care Program. AIDS and Behavior, 24(6), 1765-1775. https://doi.org/10.1007/s10461-019-02727-x

Harvard

Gunzler, D, Lewis, S, Webel, A, Lavakumar, M, Gurley, D, Kulp, K, Pile, MK, El-Hayek, V & Avery, A 2020, 'Depressive Symptom Trajectories Among People Living with HIV in a Collaborative Care Program', AIDS and Behavior, vol. 24, no. 6, pp. 1765-1775. https://doi.org/10.1007/s10461-019-02727-x