Exercise testing for assessment of heart failure in adults with congenital heart disease

Research output: Contribution to journalReview article


External Institution(s)

  • University of Pennsylvania
  • Vanderbilt University


Original languageEnglish (US)
Pages (from-to)647-655
Number of pages9
JournalHeart Failure Reviews
Issue number4
StatusPublished - Jul 1 2020


Congenital heart disease (CHD)–related heart failure is common and associated with significant morbidity, mortality, and resource utilization. In adults with CHD (ACHD), exercise limitation is often underestimated. Quantitative assessment with cardiopulmonary exercise testing (CPET) provides a comprehensive evaluation of exercise capacity and can help risk stratify patients, particularly across serial testing. CPET parameters must be interpreted within the context of the underlying anatomy, specifically for patients with either single ventricle physiology and/or cyanosis. Acknowledging differences in CPET parameters between ACHD and non-ACHD patients with heart failure are also important considerations when evaluating the overall benefit of advanced heart failure therapies. CPET testing can also guide safe exercise recommendation, including those with ACHD-related heart failure.

    Research areas

  • Adult congenital heart disease, Exercise testing, Heart failure

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