Innate Lymphoid Cells Play a Pathogenic Role in Pericarditis
Research output: Contribution to journal › Article
- Johns Hopkins University
- Institute for Clinical and Experimental Medicine
Choi et al. show a pathogenic role for innate lymphoid cells (ILCs) in IL-33-induced eosinophilic pericarditis. ILCs are required for the development of pericarditis, and group 2 ILCs (ILC2s) promote the expression of eotaxin by cardiac fibroblasts. In humans, ILCs are found higher in the pericardial fluid of patients with pericarditis compared to others.
- IL-33, Innate lymphoid cells, cardiac inflammation, eosinophils, group 2 innate lymphoid cells, mediastinum, pericarditis, serosal cavity