The Impact of Obesity in Heart Failure

Research output: Contribution to journalReview article


  • Salvatore Carbone
  • Carl J. Lavie
  • Andrew Elagizi
  • Ross Arena
  • Hector O. Ventura

External Institution(s)

  • University of Queensland
  • University of Illinois at Chicago
  • Total Cardiology Research Network


Original languageEnglish (US)
Pages (from-to)71-80
Number of pages10
JournalHeart Failure Clinics
Issue number1
StatusPublished - Jan 2020


Obesity has reached worldwide epidemic proportions, adversely impacting health on a global scale. Overweight and obesity adversely impact cardiac structure and function, affecting systolic and diastolic ventricular function. Studies and meta-analyses have documented an obesity paradox in large heart failure cohorts, where overweight and obese individuals with established heart failure have a better short- and medium-term prognosis compared with lean patients; this relationship is strongly impacted by level of cardiorespiratory fitness. There are implications for therapies aimed at increasing lean and muscle mass, and weight loss, for the prevention and treatment of compared with in patients with concomitant obesity.

    Research areas

  • Body composition, Cardiorespiratory fitness, Heart failure, Obesity, Obesity paradox

Citation formats


Carbone, S., Lavie, C. J., Elagizi, A., Arena, R., & Ventura, H. O. (2020). The Impact of Obesity in Heart Failure. Heart Failure Clinics, 16(1), 71-80.


Carbone, S, Lavie, CJ, Elagizi, A, Arena, R & Ventura, HO 2020, 'The Impact of Obesity in Heart Failure', Heart Failure Clinics, vol. 16, no. 1, pp. 71-80.